Category Medical Specialty
CCC Critical Care compendium 340

Clostridium difficile and PMC

Pseudomembranous colitis (PMC); acute inflammatory disease of colon commonly associated with antibiotic use; C. difficile implicated as a causative organism in 1970’s

CCC Critical Care compendium 340

Portopulmonary syndrome

Portopulmonary Syndrome is NOT considered contraindication to liver transplantation; affects ~20% of pre-transplant patients; usually due to increased blood flow through the lungs without increased resistance

CCC Critical Care compendium 340

Storage Lesions

Storage lesions are the adverse effects associated with the storage of blood; begins after about 2 weeks of storage and progresses with duration of storage ('RBC age')

CCC Critical Care compendium 340

Infective Endocarditis

infective endocarditis is a disease characterised by inflammation of the endocardium, typically affecting the heart valves and usually caused by infection and can be acute, subacute or chronic

CCC Critical Care compendium 340

Hepatopulmonary Syndrome

Hepatopulmonary Syndrome = hepatic dysfunction + intrapulmonary vasodilation -> gas exchange abnormalities; imbalance between intrapulmonary vasoconstriction and vasodilation at the pre- and post-capillary level

CCC Critical Care compendium 340

Tumour Lysis Syndrome

Tumour Lysis Syndrome: oncological emergency due to turnover of high cell mass malignancies resulting in severe metabolic derangement

CCC Critical Care compendium 340

von Willebrand Disease

von Willebrand Disease: commonest inherited coagulation disorder (autosomal dominant); protein involved in (1) platelet adhesion and (2) carriage of factor VIII; leads to: factor VIII deficiency, abnormal platelet adhesiveness and abnormal vascular endothelium

CCC Critical Care compendium 340

VTE Prophylaxis

Venous thromboembolism (VTE) may contribute to up to 12% of deaths in ICU and is the No.1 preventable cause of hospital death; asymptomatic events range from 10-80% in various medical and surgical groups