Digoxin Toxicity
Digoxin toxicity is characterised by gastrointestinal distress, hyperkalemia and life-threatening dysryhthmias, including increased automaticity and AV nodal blockade
Digoxin toxicity is characterised by gastrointestinal distress, hyperkalemia and life-threatening dysryhthmias, including increased automaticity and AV nodal blockade
Activated Charcoal: decontamination agent; absorbing molecules of drug on its surface -> inhibiting their absorption by as much as 50% -> excretion in faeces
Renal Literature Summaries
Optimal dose of renal replacement therapy (RRT) is controversial... the definition of dose in clinical practice is also a little controversial!
Opioid Withdrawal
Opioid Overdose: miosis; CNS depression; respiratory depression; complications of hypoxia: seizures, dysrrhythmia, brain injury
Paraquat Poisoning; highly toxic herbicide; common agent in suicide in 3rd world; leading single agent causing death from pesticide poisoning in many countries including Sri Lanka
The patient's form a heterogeneous group that requires a systematic approach based on early resuscitation where needed, risk assessment to guide further management and early consideration of the underlying psychosocial issues.
AKI is the entire spectrum of disease (mild -> severe), and can be defined as an abrupt (1 to 7 days) and sustained (more than 24 hours) decrease in kidney function. Mortality of critically patients with acute renal failure is high (50%–60%)
Acute kidney injury (AKI) is a common problem in the critically ill associated with increased morbidity and mortality
Renal Transplant; commonest transplant; anastamosed to common iliac artery and vein in the pelvis. the ureter is plumbed into the bladder; allows ease of access for palpation and biopsy
AKI can be defined as an abrupt (1 to 7 days) and sustained (more than 24 hours) decrease in kidney function. The ADQI formulated the RIFLE criteria in 2004 to allow for AKI to be objectively and uniformly defined.