Charcot-Marie-Tooth disease


Charcot-Marie-Tooth disease (spinal form of muscular atrophy) is the commonest disease within a group of conditions called Hereditary Motor and Sensory Neuropathies (HMSN).

Virchow, Schultze, and others had reported cases of peroneal atrophy previously, but in 1886 medical knowledge had advanced sufficiently to accept this entity as a nosologic addition.

The simultaneous publications by Charcot and Marie in France and by Tooth in England do not attest to coincidence but to the fact that the medical world was ready to appreciate the finer clinical distinctions existing within the large group of progressive muscular atrophies.

History of Charcot-Marie-Tooth disease

Associated Persons

Alternative names
  • Charcot-Marie-Tooth-Hoffman disease


Historical articles

Review articles

eponymictionary CTA


the names behind the name

BA MA (Oxon) MBChB (Edin) FACEM FFSEM. Emergency physician, Sir Charles Gairdner Hospital.  Passion for rugby; medical history; medical education; and asynchronous learning #FOAMed evangelist. Co-founder and CTO of Life in the Fast lane | Eponyms | Books | Twitter |

Leave a Reply

This site uses Akismet to reduce spam. Learn how your comment data is processed.