25 year old with a history of sickle cell disease presents with severe back and bilateral leg pain. Describe and interpret the progression of her CXR’s

Acute chest syndrome day 1

Patient now febrile, dyspoeic, tachypnoeic and tachycardic

Acute chest syndrome day 3

Describe and interpret this CXR


The CXR on presentation looked normal. This is the case for around 50% of hospitalised SCD patients who go on to develop Acute Chest syndrome.

Note: Resolution of CXR findings often lag behind clinical improvement

Acute chest syndrome CT

Authors: Gabriela Rivera Camacho MD and Mark Kastner, MD
Guest Editors: Ifeyinwa Osunkwo MD and Padmaja Veeramreddy, MD


Michael A. Gibbs, MD, FACEP, FAAEM. Professor and Chair, Department of Emergency Medicine at Carolinas Medical Center & Levine Children’s Hospital | EMGuidewire |

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