Fuchs corneal dystrophy
Description
Fuchs endothelial corneal dystrophy is characterised by bilateral endothelial cell loss. Examination signs include:
- central guttata – the presence of irregular warts or excrescences on Descemet membrane secreted by abnormal endothelial cells
- tiny dark spots caused by distribution of the regular endothelial mosaic which progress to a ‘beaten metal appearance’
History of Fuchs corneal dystrophy
1910 – Ernst Fuchs (1851-1930) reported 13 cases of central corneal clouding, loss of corneal sensation and formation of epithelial bullae which he labelled as ‘dystrophia epithelialis corneae’
1913 – Exacerbation of the disease post cataract surgery was noted
1920’s – The pathophysiology of Fuchs’ dystrophy was recognised as primarily a disease of the corneal endothelium, with Alfred Vogt a Swiss Ophthalmologist first using the term ‘central guttata’ in 1921
Associated Persons
- Ernst Fuchs (1851-1930)
Alternative names
- Fuchs’ endothelial-epithelial dystrophy
Controversies
Did they first describe or popularise or plagiarise?
References
Historical references
- List
Eponymous term review
eponymictionary
the names behind the name