CCC Critical Care compendium 340
Cognitive Dispositions to Respond

Reviewed and revised 8 December 2014 OVERVIEW Cognitive Dispositions to Respond (CDRs) or cognitive biases are:  “Predictable tendencies, or biases, to react to contextual clues that are largely unconscious and may contribute to flaws in reasoning; a mental state that embraces…

CCC Critical Care compendium 340
Fluid bolus therapy

Fluid bolus therapy is widely administered to patients with undifferentiated hypotension and for patients with severe sepsis

CCC Critical Care compendium 340
Fluid Challenge

The fluid challenge (FC) aims at identifying patients in whom fluid administration improves haemodynamics (known as "fluid responsiveness")

CCC Critical Care compendium 340
Adaptive Trial Designs

An adaptive clinical trial involves a study design in which key characteristics are adjusted while enrollment in the trial is ongoing using prospectively defined decision rules and in response to information arising from the data accumulating in the trial