Pandemic Sepsis Research • LITFL • CODA ZERO

Pandemic Sepsis Research through a Covid-19 lens – Are we failing? with Derek C. Angus

Blanket standards applied in research design, particularly those applied traditionally in a “peace time” setting are worth being carefully examined for their relevance now in this pandemic “war time” setting so that we don’t hog-tie ourselves with irrelevant and unhelpful regulations.

At the same time, we don’t want the ‘wild wacky west’.

Everyone is under pressure in research to move quickly, but we need to ensure that if we change standards we do so intelligently so that the choices we make for more pragmatic design are perfect.

The pandemic has shown how as experts we are so narrow minded.

It is sad how little we really listen to each other.

On a large scale COVID-19 has really shown up that many of us in medicine have become super-specialised, and it is very hard for us to think across different domains and to think with any range.

The Presentation

The Podcast

The Speaker

Dr Derek C. Angus is a physician scientist and healthcare administrator. Distinguished Professor and the Mitchell P. Fink Endowed Chair at the Department of Critical Care Medicine, University of Pittsburgh School of Medicine. He is also physician director of the UPMC ICU Service Center, responsible for the organization and delivery of critical care services across the 40-plus hospital system.

Dr. Angus’ research interests include translational, clinical, and health services research in the fields of sepsis, pneumonia, and multisystem organ failure, as well as optimal acute care delivery. He has a particular interest in novel trial designs for precision medicine and strategies to enable a true rapid learning health system, specifically REMAP-CAP.

Dr. Angus has led several large NIH-funded multicenter studies, published several hundred papers, and received numerous national and international awards for his work. He is also the critical care editor for JAMA.

Coda CURE 2020