Prof. Dr. Ruth Illig (1924 – 2017) was a German pediatric endocrinologist.
Illig was one of the pioneers of European pediatric endocrinology and an enthusiastic campaigner for the improvement of the health of children and adolescents, not only in Europe, but also globally.
She made a major contribution to the clinical detection, biochemical confirmation, and treatment of growth hormone deficiency together with Andrea Prader (1919-2001). The eponymous term ‘Illig Syndrome’ was originally given to describe growth hormone deficiency.
Prof Illig also made vital contributions to the application of TSH assays for newborn hypothyroidism screening and instigation of early treatment with thyroid hormones. She conducted studies both on screening methodology, and long-term follow-up for neonates with hypothyroidism. Aware that economically disadvantaged countries could not afford a neonatal screening program she founded a charitable organisation in her retirement to finance national screening programs in countries such as Bulgaria.
- Born 12 November 1924 in Nuremberg, Germany
- After the war she moved to Switzerland and commenced her medical training in Bern and Zurich
- 1956 Paediatric residency at the University Children’s Hospital (Kinderspital) in Zurich under Guido Fanconi (1892–1979)
- 1960-1987 Pediatrician at the Kinderspital, Zurich. Founded the endocrinology laboratory, in which she introduced new methods for determining growth hormone and insulin.
- 1965 – One of the founding members of the European Society for Paediatric Endocrinology (ESPE)
- 1976 – Developed a rapid detection method for hypothyroid screening in the newborn. Developed the first nationwide screening program for congenital hypothyroidism in Europe. After a pilot study, Illig started the full program in Switzerland on 1 January 1977.
- 1977 – First female professor at the Medical Faculty of the University in Zurich
- 1986 – Established and financed an institution for children with visual impairment in Switzerland
- 1986 – President of the ESPE 25th Annual Meeting in Zurich
- 2006 – ESPE Outstanding Clinician Award for her many years of dedication to paediatric endocrinology
- Died 24 June 2017
Illig syndrome: Isolated growth-hormone deficiency affecting both sexes
- Prader A, Illig R, Szeky J, Wagner H. The effect of human growth hormone in hypopituitary dwarfism. Arch Dis Child. 1964;39(208):535-544.
- Illig R. Growth hormone antibodies in patients treated with different preparations of human growth hormone (HGH). J Clin Endocrinol Metab. 1970;31(6):679-688
- Illig R, Krawczyńska H, Torresani T, Prader A. Elevated plasma TSH and hypothyroidism in children with hypothalamic hypopituitarism. J Clin Endocrinol Metab. 1975;41(4):722-728.
- Illig R, Laron Z, Visser HK. From the Paediatric Endocrinology Club to the European Society for Paediatric Endocrinology: the early years of ESPE. Pediatr Endocrinol Rev. 2011;9(1):417-421
- ESPE Newsletter. 2006; 5: 2
- Grüters-Kieslich A, Torresani T, Konrad D. In Memoriam: Ruth Illig, MD (1924-2017). Pediatr Endocrinol Rev. 2017;15(1):2-3.
- Obituary: Prof. Dr. Ruth Illig. Int. J. Neonatal Screen. 2017; 3(3): 18
- Prof. Dr. Ruth Illig. Universität Zürich
- Bibliography. Illig, R. WorldCat Identities
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