Alternate names: Glinski syndrome; Reye syndrome; and Sheehan syndrome apply to necrosis of the pituitary during the postpartum period. Simmonds syndrome which is unrelated to postpartum complications


1913 – Leon Konrad Glinski (1870-1918) was a Polish physician

1914 – German physician, Morris Simmonds (1855-1925) recognised the clinical features were associated with destruction of the anterior lobe of the pituitary; case described in a patient with severe cachexia. Sometimes called Simmonds syndrome which is unrelated to postpartum complications

1928 – Reye

1937 – Sheehan

1949 – Sheehan and Vincent Kirwan Summers (1914-1975) published in the Quarterly Journal of Medicine on the syndrome of hypopituitarism. The paper showed convincingly that emaciation and premature senility (previously considered to be essential for the diagnosis of pituitary insufficiency), were not features of the syndrome. This paper, rather than Sheehan’s earlier papers on pituitary necrosis, led to the syndrome of post-partum pituitary necrosis becoming known as Sheehan syndrome

Associated Persons

Alternative names
  • Glinski syndrome; Reye syndrome; and Sheehan’s syndrome
  • Simmonds syndrome


Did they first describe or popularise or plagiarise?


Historical references

Eponymous term review



the names behind the name

Doctor in Australia. Keen interest in internal medicine, medical education, and medical history.

BA MA (Oxon) MBChB (Edin) FACEM FFSEM. Emergency physician, Sir Charles Gairdner Hospital.  Passion for rugby; medical history; medical education; and asynchronous learning #FOAMed evangelist. Co-founder and CTO of Life in the Fast lane | Eponyms | Books | Twitter |

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