Diffuse Toxic Goitre
The problem of nomenclature of diffuse toxic goitre (Parry, Graves or Basedow disease) remains an unsettled one. So lets review the chronological history of eponymous aetiology for toxic goitre/exophthalmic goitre
The problem of nomenclature of diffuse toxic goitre (Parry, Graves or Basedow disease) remains an unsettled one. So lets review the chronological history of eponymous aetiology for toxic goitre/exophthalmic goitre
Karl Adolph von Basedow (1799 – 1854) was a German general practitioner, surgeon and obstetrician. Described Basedow (Graves) disease 1840
Albrecht von Gräfe (1828 – 1870) was a German ophthalmologist. Founder of scientific ophthalmology, Graefe sign (1864)
Graves disease: Autoimmune disease that affects the thyroid. A form of hyperthyroidism manifesting the triad of goitre, exophthalmos and pretibial myxoedema.
Möbius sign: Diagnostic test in patients with Morbus Basedow (Graves disease) - the inability to maintain ocular convergence in the presence of hyperthyroidism.