Tag Toxidrome
CCC Critical Care compendium 340

Serotonin Syndrome CCC

Serotonin syndrome results from drug-induced over-stimulation of serotonin receptors in the CNS and is characterized by a triad of CNS dysfunction, autonomic disturbance and neuromuscular effects; aka serotonin toxicity
Toxicology Flashcards 340

Anticholinergic Toxidrome

Anticholinergic Toxidrome was one of the first flashcards I designed. I wanted to make a play on the old mnemonic: mad as a hatter, hot as hell, red as a beat, dry as a bone, and blind as a bat.
Toxicology Flashcards 340

Cholinergic Toxidrome

Cholinergic Toxidrome was the first flashcard I created, and forever encapsulates Travis as “the guy on the toilet”
Toxicology-Conundrum-340 256

A Fumbling, Mumbling Mess!

A 41-year old man is brought to ED after becoming drowsy while in police custody. He states that he has taken an overdose of diazepam tablets prior to being arrested. A puzzling case of drug-induced delirium. Can you solve the mystery?
CCC Critical Care compendium 340

Sedative Toxidrome

Sedative toxidrome: agents - opioids; benzodiazepines; barbiturates; baclofen (may mimic brain death, suspect in MS patients); clonidine (mimics opioid toxidrome with marked bradycardia and hypotension) GHB
CCC Critical Care compendium 340

Sympatholytic toxidrome

True sympatholytic agents (e.g. alpha-blockers like phentolamine, and vasodilatory agents such as GTN, SNP, etc)≥ Also beta-blocker; ca2+ blocker; clonidine; digoxin
CCC Critical Care compendium 340

Malignant Hyperthermia CCC

Malignant Hyperthermia = pharmacogenetic disease of skeletal muscle induced by exposure to certain anaesthetic agents; incidence 1:5,000 -> 1:65,000 anaesthetics (suspected); mutation in the gene coding for the ryanodine receptor
CCC Critical Care compendium 340

Hyperthermia-associated toxidromes

Toxidromes associated with hyperthermia may be difficult to distinguish: serotonin syndrome; anticholingeric syndrome; sympathomimetic syndrome; neuroleptic malignant syndrome; malignant hyperthermia