Month January 2019
CCC Critical Care compendium 340

Immediate Post-ROSC Management

A team-based approach to the management of the post-ROSC patient focuses on initiation of therapeutic hypothermia, treatment of the underlying cause with transfer to the cath lab where appropriate, and management of the post-cardiac arrest syndrome.

CCC Critical Care compendium 340

Deresuscitation and Positive Fluid Balance

Deresuscitation specifically refers to 'Late Goal Directed Fluid Removal (LGFR)', which involves "aggressive and active fluid removal by means of diuretics and renal replacement therapy with net ultrafiltration" (Malbrain et al, 2014)

CCC Critical Care compendium 340

Glycocalyx in Critical Illness

The endothelial glycocalyx (EG) is a thin proteinaceous layer previously thought to be inert, that is now thought to play a key role in vascular integrity and function. The glycocalyx has potential as a novel therapeutic target

CCC Critical Care compendium 340

Chronic Graft Versus Host Disease

Chronic Graft vs Host Disease is organ dysfunction occurring > 100 days post transplantation; distinct clinical syndrome from acute GVHD; pathophysiology poorly understood

CCC Critical Care compendium 340

Encephalitis

Encephalitis an acute encephalopathy due to an inflammatory cause
Underlying causes are numerous and may be infectious or non-infectious, many of which lack effective therapies

CCC Critical Care compendium 340

Stroke Thrombolysis

Stroke Thrombolysis: thrombolysis for acute ischaemic stroke is a controversial intervention; it is supported by a number of guidelines and in general is viewed favourably by the neurological community

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Mirizzi syndrome

Mirizzi syndrome or extrinsic biliary compression syndrome, is a rare complication of cholelithiasis. Mirizzi syndrome is characterised by obstruction of the common bile duct (CBD), secondary to mechanical compression caused by the impaction of one or multiple gallstones in the neck of the gallbladder or cystic duct