Aubrey Otis Hampton (1900 – 1955) was an American Radiologist.
He specialised in chest radiology and pulmonary pathology, publishing numerous original radiological observations in pulmonary infarction, lipoid pneumonia, middle lobe diseases, and gastrointestinal pathologies.
Hampton is eponymously affiliated with Hampton hump (1940), describing radiograph findings of pulmonary embolism; and Hampton line (1956) on barium radiological studies to confirm benign gastric ulcers.
- Born 1900 in Copeville, Texas
- 1925 – Graduated medical studies from Baylor University Medical School in Texas
- 1926-42 – Radiology training at Massachusetts General Hospital, Boston
- 1941 – Chief of radiology, Massachusetts General Hospital
- 1942-45 – Chief of radiology during World War II at Walter Reed Army Hospital in Washington, DC, then becoming radiological consultant following the war
- 1945 – Worked at Garfield Hospital Department of Radiology in Washington
- Designed a fellowship for radiologic pathology at the Armed Forces Institute of Pathology, which was named the ‘Aubrey O. Hampton Fellowship of Radiological Pathology’ by the American Roentgen Ray Society in honour of his services
- Died 17 July 1955 in Weare, New Hampshire
Hampton hump (1940)
The Hampton hump is a well-defined pulmonary pleural based opacity representing haemorrhage and necrotic lung tissue in a region of pulmonary infarction caused by acute pulmonary embolism. The medial margin of the opacity frequently demonstrates a medial curved ‘hump‘ directed towards the heart.
22% sensitivity, 82% specificity, 29% PPV, 76% NPV PIOPED 1993
Hampton line (1956) – on barium swallow, describes a well-defined, thin lucent line at the base of the gastric ulcer suggesting a benign lesion, which reflects the undermining of the submucosa, with preservation of the relatively resistant mucosa
- Hampton AO, Castleman B. Correlation of postmortem chest teleroentgenograms with autopsy findings with special reference to pulmonary embolism and infarction. American journal of roentgenology and radium therapy 1940; 43(1): 305-326 [Hampton hump]
- Hampton AO, Schumacher FV. Radiographic differentiation of benign and malignant gastric ulcers. Ciba Clin Symp. 1956 Sep-Oct;8(5):161-71. [Hampton line]
- Miller RB, Hampton AO. Anomalies of the gastrointestinal tract; a review of the literature and report of two unusual cases. N Engl J Med. 1950 Aug 17;243(7):241-7.
- Goulard A Jr, Hampton AO. Correlation of the clinical, pathological and roentgenological findings in diverticulitis. Am J Roentgenol Radium Ther Nucl Med. 1954 Aug;72(2):213-21.
- Pack GT, Hampton AO et al The relationship of gastric ulcer to gastric cancer. Med Ann Dist Columbia. 1953 Apr;22(4):185-92.
- Hampton AO, Bickham CE Jr, Winship T. Lipoid pneumonia. Am J Roentgenol Radium Ther Nucl Med. 1955 Jun;73(6):938-49.
- Linton OW. Radiology at Massachusetts General Hospital 1896-2000. General Hospital Corporation. 2001
- Schatzki R, Lingley JR. Aubrey O. Hampton, 1900-1955. Am J Roentgenol Radium Ther Nucl Med. 1956 Feb;75(2):396-7.
- Video: 50th Aubrey O. Hampton Lecture Celebration. Department of Radiology at Mass General Hospital
- Maizlin ZV, Cooperberg PL, Clement JJ, Vos PM, Coblentz CL. People Behind Exclusive Eponyms of Radiologic Signs (Part I) Can Assoc Radiol J. 2009; 60(4): 201-212.
- Bibliography. Hampton, Aubrey. WorldCat Identities
- Cadogan M. CXR eponyms in pulmonary embolism. LITFL
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