Aubrey Hampton
Aubrey Otis Hampton (1900-1955) was an American Radiologist.
Hampton trained under George W. Holmes at Massachusetts General Hospital (MGH), where he later became chief of radiology and was associated with Harvard Medical School. His principal scientific interests included chest radiology and pulmonary pathology, with important work on pulmonary infarction, middle-lobe disease and lipoid pneumonia, as well as gastrointestinal and musculoskeletal radiology. His name is associated with the Hampton hump of pulmonary infarction and Hampton line in benign gastric ulceration.
During and after the Second World War, Hampton had an important organisational role in American radiology. He served as chief of the radiological service at Walter Reed Army Hospital and the Veterans Administration, influencing design, equipment and staffing of radiology departments across the VA hospital system. He helped establish a fellowship in radiological pathology at the Armed Forces Institute of Pathology, later named the Aubrey O. Hampton Fellowship of Radiological Pathology in his honour.
Hampton was remembered by colleagues as an exceptionally intuitive clinical radiologist. Although he disliked formal didactic teaching, his weekly radiology seminars with George Holmes at MGH became highly regarded. Lingley and Schatzki particularly highlighted his independent approach to diagnosis and his insistence that students think critically rather than depend entirely on “textbook wisdom”.
Biography
- Born September 10, 1900 in Copeville, Texas, son of Calvin Wade Hampton and Mary Catherine Hornbuckle Hampton.
- 1925 – Graduated MD from Baylor University Medical School. Interned in Dallas at St Paul’s Sanitarium and Parkland Hospital and briefly practised general medicine before entering radiology.
- 1926 – Moved to Massachusetts General Hospital, Boston, to train in radiology under George W. Holmes.
- 1927–1928 – Assistant resident in radiology at MGH. Later joined the radiology staff, serving as a radiologist from 1928 to 1940. Assistant professor of radiology at Harvard Medical School.
- 1940 – With Benjamin Castleman, published Correlation of postmortem chest teleroentgenograms a radiographic–pathological study associated with the eponymous Hampton hump.
- 1941 – Succeeded Holmes as chief of the Department of Radiology at Massachusetts General Hospital.
- 1942–1945 – Served as a colonel in the US Army Medical Corps and chief of the Radiological Service at Walter Reed Army Hospital, Washington, DC.
- 1946 – Joined the Washington radiology practice of Groover, Christie and Merritt and headed the Department of Radiology at Garfield Memorial Hospital. Maintained association with Walter Reed as radiological consultant
- 1947 – Appointed Chief Consultant in Radiology to the Medical Director of the Veterans Administration. Influenced the construction, equipment specifications and staffing of VA radiology departments nationally. His recommendations also influenced post-war manufacture of radiological equipment.
- 1948 – Consultant to the clinics of the National Institutes of Health and representative of the American Roentgen Ray Society to the National Research Council. Instrumental in establishing and maintaining the radiological pathology fellowship at the Armed Forces Institute of Pathology.
- Died on July 17, 1955 from a cerebrovascular accident at his farm in Weare, New Hampshire.
- 1956 – The American Roentgen Ray Society posthumously named the AFIP fellowship the Aubrey O. Hampton Fellowship of Radiological Pathology. His paper with F. V. Schumacher on differentiating benign from malignant gastric ulcers, associated with Hampton line, published posthumously.
Medical Eponyms
Hampton hump (1940)
Hampton hump describes a peripheral, pleural-based pulmonary opacity caused by haemorrhagic pulmonary infarction secondary to pulmonary embolism.
In 1940, Hampton and Benjamin Castleman published their radiographic–pathological study of pulmonary embolism and infarction, correlating postmortem chest radiographs with gross and microscopic pathology. They described peripheral infarcts of variable shape, with a characteristic convex medial or cardiac margin capable of producing the later “hump-shaped” appearance.
The original paper did not use the term Hampton’s hump. The eponymous term was established in 1958 by Felix Fleischner.
Hampton line (1956)
Hampton line is a thin, sharply defined radiolucent line across the neck of a contrast-filled benign gastric ulcer, representing undermining of the submucosa with preservation of the relatively resistant mucosa.
Major Publications
- Hampton AO, Castleman B. Correlation of postmortem chest teleroentgenograms with autopsy findings with special reference to pulmonary embolism and infarction. American journal of roentgenology and radium therapy 1940; 43(1): 305-326 [Hampton hump]
- Hampton AO, Schumacher FV. Radiographic differentiation of benign and malignant gastric ulcers. Ciba Clin Symp. 1956 Sep-Oct;8(5):161-71. [Hampton line]
- Miller RB, Hampton AO. Anomalies of the gastrointestinal tract; a review of the literature and report of two unusual cases. N Engl J Med. 1950 Aug 17;243(7):241-7.
- Goulard A Jr, Hampton AO. Correlation of the clinical, pathological and roentgenological findings in diverticulitis. Am J Roentgenol Radium Ther Nucl Med. 1954 Aug;72(2):213-21.
- Pack GT, Hampton AO et al The relationship of gastric ulcer to gastric cancer. Med Ann Dist Columbia. 1953 Apr;22(4):185-92.
- Hampton AO, Bickham CE Jr, Winship T. Lipoid pneumonia. Am J Roentgenol Radium Ther Nucl Med. 1955 Jun;73(6):938-49.
- Hampton AO, Schumacher FV. Radiographic differentiation of benign and malignant gastric ulcers. Ciba Clin Symp. 1956 Sep-Oct;8(5):161-171
References
Biography
- Schatzki R, Lingley JR. Aubrey O. Hampton, 1900-1955. Am J Roentgenol Radium Ther Nucl Med. 1956 Feb;75(2):396-7.
- Linton OW. Radiology at Massachusetts General Hospital 1896-2000. General Hospital Corporation. 2001
- Maizlin ZV. Aubrey Otis Hampton in: Wonders of Radiology. 2010: 62-65
Eponymous terms
- Maizlin ZV, Cooperberg PL, Clement JJ, Vos PM, Coblentz CL. People Behind Exclusive Eponyms of Radiologic Signs (Part I) Can Assoc Radiol J. 2009; 60(4): 201-212.
- Cadogan M. CXR eponyms in pulmonary embolism. LITFL
eponymictionary
the names behind the name
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