Herndon DN et al. A comparison of conservative versus early excision. Therapies in severely burned patients. Ann Surg. 1989 May;209(5):547-52; discussion 552-3. [PMC1494069]
n = 85
inclusion criteria: > 30% TBSA burn
early excision VS topical antimicrobials + skin grafting after spontaneous eschar separation -> mortality from burns without inhalational injury decreased by early excision -> reduces hypermetabolic response to burns -> reduces infection -> improves cosmesis
Herndon DN, Hart DW, Wolf SE, Chinkes DL, Wolfe RR. Reversal of catabolism by beta-blockade after severe burns. N Engl J Med. 2001 Oct 25;345(17):1223-9. [PMID 11680441]
n = 25
inclusion: children, > 40% TBSA
propanolol PO vs placebo -> significant reduction in heart rate, resting energy expenditure -> increased muscle-protein balance
Navar PD, Saffle JR, Warden GD. Effect of inhalation injury on fluid resuscitation requirements after thermal injury. Am J Surg. 1985 Dec;150(6):716-20. [PMID 4073365]
After finishing his medical degree at the University of Auckland, he continued post-graduate training in New Zealand as well as Australia’s Northern Territory, Perth and Melbourne. He has completed fellowship training in both intensive care medicine and emergency medicine, as well as post-graduate training in biochemistry, clinical toxicology, clinical epidemiology, and health professional education.
He is actively involved in in using translational simulation to improve patient care and the design of processes and systems at Alfred Health. He coordinates the Alfred ICU’s education and simulation programmes and runs the unit’s education website, INTENSIVE. He created the ‘Critically Ill Airway’ course and teaches on numerous courses around the world. He is one of the founders of the FOAM movement (Free Open-Access Medical education) and is co-creator of litfl.com, the RAGE podcast, the Resuscitology course, and the SMACC conference.
His one great achievement is being the father of two amazing children.