Franz Wiesbauer explains the relationship between pH, HCO3 and pCO2 and a simple rule which will help you decide whether the primary problem is respiratory or metabolic in nature.
Franz Wiesbauer explains how to differentiate between metabolic acidaemia caused by a loss of bicarbonate and that caused by the addition of acid.
Franz Wiesbauer looks at acid-base compensation and some super-simple rules that will help you decide whether compensation is adequate or not.
29 yr old male presents complaining of vomiting, dizziness and felling 'vague'. Describe and interpret this ECG. LITFL Top 100 ECG
This is quick reference page to acid base disorders in toxicology and osmolar gaps. Zeff a toxicologist from Melbourne talks through his approach and the errors that can occur with osmolar and anion gaps.
Arterial blood gas analysis is used to determine the adequacy of oxygenation and ventilation, assess respiratory function and determine the acid–base balance.
Osmolar Gap: Osmolar gap = Osmolality (measured) - Osmolarity (calculated): NOTE: is a pragmatic clinical aid - the units are different (osmolality =mOsm/kg and osmolarity = mOsm/L) so it doesn't make mathematical sense!
Metabolic Alkalosis DDx
Respiratory Acidosis DDx
Metabolic acidosis DDx
OVERVIEW Anion Gap = Na+ – (Cl- + HCO3-) The Anion Gap (AG) is a derived variable primarily used for the evaluation of metabolic acidosis to determine the presence of unmeasured anions The normal anion gap depends on serum phosphate…
Metabolic acidosis can occur in both acute and chronic renal disorders; the anion gap may be elevated, due to uraemic acidosis; the anion gap may be normal, due to renal tubular acidosis (RTA)