Category CCC

The LITFL Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care.

CCC Critical Care compendium 340

Traumatic Brain Injury (TBI) Assessment

OVERVIEW TBI assessment involves: HISTORY General (AMPLE) Specifically: EXAMINATION Specifically in TBI assess: Evidence of base of skull fracture: Look for evidence of trans-tentorial herniation: Look for evidence of underlying causes and complications INVESTIGATIONS Bedside Laboratory Imaging References and Links

CCC Critical Care Compendium 680

Pseudofracture DDx

There are multiple reasons why lucent lines may appear in bones, or why bone contours may appear abnormal, mimicking fractures.

CCC Critical Care Compendium 680

Bronchiectasis DDx

Bronchiectasis is a suppurative lung disease characterised by the presence of permanently and abnormally widened (dilated) bronchial airways. Bronchiectasis may be the end result of a number of etiological processes.

CCC Critical Care compendium 340

Sepsis Biomarkers

Reviewed and revised 20 December 2015 OVERVIEW At least 178 different sepsis biomarkers have been described in the published medical literature, reflecting the complex pathophysiology of sepsis e.g. coagulation, complement, contact system activation, inflammation, and apoptosis also biomarkers of complications, e.g.…

CCC Critical Care Compendium 680

Arthritis DDx

Arthritis is inflammation of a joint (redness, warmth, pain, swelling, loss of function) that may be acute or chronic, and affect one or multiple joints.

CCC Critical Care compendium 340

Lithium Toxicity

Lithium: acute overdose is usually benign if adequate hydration is maintained and renal function is normal; chronic toxicity can be difficult to manage and result in devastating neurotoxicity

CCC Critical Care compendium 340

Methylene Blue

CLASS MECHANISM OF ACTION (1) low concentrations: methylene blue -> NADPH-dependent reduction to leucomethylene blue (due to action of methaemoglobin reductase) -> reduces methaemoglobin -> Hb(2) high concentrations: methylene blue -> converts ferrous iron of reduced Hb to ferric ion…

CCC Critical Care Compendium 680

Hilar adenopathy DDx

Hilar lymphadenopathy, seen on chest x-ray or chest CT, can be classified as unilateral or bilateral, and if bilateral as symmetrical or asymmetrical.