Category CCC

The LITFL Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care.

CCC Critical Care Compendium 680

Melioidosis

Melioidosis is a severe infectious disease caused by the bacterium Burkholderia pseudomallei. It is widespread in Southeast Asia and Northern Australia, with increasing recognition in other tropical and subtropical regions. It presents with a wide range of clinical manifestations, from localized infections to severe sepsis and septic shock.

CCC Critical Care Compendium 680

Malignant Hyperthermia

Malignant Hyperthermia = pharmacogenetic disease of skeletal muscle induced by exposure to certain anaesthetic agents; incidence 1:5,000 -> 1:65,000 anaesthetics (suspected); mutation in the gene coding for the ryanodine receptor