Antidotes are agents that counteract the effects of a toxic agent on the body. They do not primarily affect the systemic absorption or removal of toxic agents from the body (i.e. decontamination and enhanced elimination respectively)
In specialist centres, extracorporeal membrane oxygenation (ECMO) is a now a mainstay of the management of cardio/respiratory failure refractory to other measures. However, much of the clinical information required to care for ECMO patients at the bedside remains inaccessible to…
WHAT IS EUBOXIA? ‘Euboxia‘ is the pathophysiological state whereby ‘all boxes on a pathology print-out are in the normal range’ (Reade, 2009). LITFL — Don’t put your patient in a box Reade MC (2009). Should we question if something works…
A 30 year-old female was BIBA to the ED following a seizure. She was running a marathon in hot weather. Nearing the end, after 5 hours running, she was seen fall to the ground and had a generalised tonic-clonic seizure.
Exercise-associated Hyponatremia HYPOnatremia Interpretation Seizures, hyponatremia and ADH Cause of HYPOnatraemia Definition: Serum sodium <130mEq/l Cause: Excess of Water relative to Sodium Affects: 1% of hospital population Hypovolemic (Na deficit in xs of water deficit) (test urine sodium) RENAL (urinary…
Deconditioning occurs as a result of restricted physical activity, and reduces the ability to perform work; can occur with relatively short periods of immobility; affected by age, premorbid state, specific illness and medications
An open fracture is a fracture that communicates with an overlying disruption of the skin and soft tissues. They are also called compound fractures. Open fractures are potentially limb-threatening injuries.
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