Oozing from a Venepuncture Site
An approach to the patient with persistent bleeding from a venepuncture site
The LITFL Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care.
An approach to the patient with persistent bleeding from a venepuncture site
OVERVIEW Lupus Anticoagulants -> result in acquired hypercoagulability due to poorly understood actions ? alteration of the regulation of haemostasis and endothelial cell injury ASSOCIATIONS MANAGEMENT (1) APTT (2) dilute Russell viper venom time (3) silica clotting time(4) kaolin clotting…
Isolated Elevated APTT
Thyroid Storm: life threatening exacerbation of hyperthyroid state with 1 or more organ dysfunction
Pheochromocytoma: paraganglioma -> catecholamine producing tumours; associated with: MEN, von Hippel-Lindau syndrome, neurofibromatosis and familial paragangliomas
Myxoedema Coma: extreme form of hypothyroidism; high mortality
Haemolytic uraemic syndrome (HUS) is a clinically similar condition to TTP; in HUS (unlike TTP): renal failure > neurological symptoms
Haematology Literature Summaries
Reviewed and revised 27 October 2016 OVERVIEW Definition Haemolytic anaemia is anemia due to shortened survival of red blood cells (RBCs) in the circulation Normal RBC lifespan is about 120 days, therefore it is useful to think of hemolytic anemia…
almost all haematological malignancies are curable with modern treatments such as chemotherapy, radiotherapy, immunotherapy and bone marrow transplantation
Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by the intravascular activation of coagulation with loss of localization arising from different causes
antiphospholipid syndrome (APS) is diagnosed by the occurrence of thrombosis or pregnancy morbidity in combination with detectable antibodies