Category CCC

The LITFL Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care.

CCC Critical Care compendium 340

Adenosine

Adenosine: short acting anti-arrhythmic; naturally occurring purine nucleoside. Epression of SA & AV nodal activity; antagonises cAMP-mediated catecholamine stimulation of ventricular muscle

CCC Critical Care compendium 340

History of Emergency Medicine

The history of emergency medicine in Australia and New Zealand has paralleled developments in the United States, Canada and the United Kingdom, although the models of emergency care exhibit some variation between systems, and between institutions within these systems

CCC Critical Care compendium 340

Surrogate outcomes

Surrogate outcomes are biomarkers intended to substitute for a clinical endpoint and expected to predict clinical benefit or harm based on epidemiologic, therapeutic, pathophysiologic, or other scientific evidence

CCC Critical Care compendium 340

Lung Transplant

Can have one or both lungs transplanted depending on disease process. Single lung transplants only suitable for non-infective conditions that will not go on to damage new lung, with no cardiac disease

CCC Critical Care compendium 340

Negative Pressure Pulmonary Oedema

Negative pressure pulmonary edema (NPPE) is a form of noncardiogenic pulmonary edema (PE) that results from the generation of high negative intrathoracic pressure (NIP) needed to overcome upper airway obstruction

CCC Critical Care compendium 340

Oxidative Stress in Critical Illness

Oxidative stress is refers an imbalance between production of reactive oxygen species and the protection of antioxidants, due to the accumulation of free radicals and/or the inability of antioxidants to counter their accumulation or effects.

CCC Critical Care compendium 340

Intensive Care Outcomes

Appropriate outcome measures is vitally important in ICU research: e.g. ICU mortality; hospital mortality; 90 day mortality; 1 year functional outcome

CCC Critical Care compendium 340

Human Factors

Human failures rather than technical failures are the greatest threat to complex and potentially hazardous systems such as healthcare systems.

CCC Critical Care compendium 340

Community Acquired Pneumonia

Community Acquired Pneumonia: Streptococcus pneumonia (most common organism); other causes: Mycoplasma pneumoniae, Chlamydophila pneumoniae and Legionella, Haemophilus influenzae (in COPD)

CCC Critical Care Compendium 680

Liver Function Tests

Liver Function Test Analysis including Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT), Alkaline Phosphatase (ALP) Lactate Dehydrogenase (LDH), Gamma Glutamyl Transferase (GGT)