Cocaine-related Chest Pain
Cocaine is a recreational drug with sympathomimetic effects in additional to being a sodium channel blocker. Cocaine can induce acute coronary syndromes through vasoconstriction, atheroma rupture and/ or dissection
Category CCC
The LITFL Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care.
Cocaine Toxicity
Cocaine Toxicity potentially life-threatening sympathomimetic syndrome with sodium channel blockade.
Sodium Channel Blocker Toxicity
AGENTS NB. phenytoin and sodium valproate do not usually present with features of sodium channel blockade in overdose. CLINICAL FEATURES INVESTIGATIONS SPECIFIC MANAGEMENT AND TRIGGERS FOR INTERVENTION References and Links
Sodium Valproate Overdose
Sodium valproate is a commonly used anti-epileptic drug, that come sin standard and enteric coated forms. Toxicity is characterised by metabolic failure, resulting in multi-organ dysfunction and cerebral edema
Oxygen and Carbon Dioxide Retention in COPD
Excessive oxygen administration can lead to hypercapnic respiratory failure in some COPD patients. COPD patients with more severe hypoxemia are at higher risk of CO2 retention from uncontrolled O2 administration
Compare and Contrast Template
OVERVIEW In the FCICM exam this means ‘describe similarities and differences (e.g. in table form)’ useful to base structure on the key features of the alternatives TEMPLATE ‘AEIOU’ Availability and cost Evidence and place in guidelines Information given (vs gold…
Cholinergic Syndrome
Cholinergic Toxidrome
High Volume Haemofiltration
High volume haemofiltration (HVH) is CRRT where the filtration rate is large - aka “high-volume,” “high intensity,” or “high flow”
Initial Management of Sepsis
Reviewed and revised 17 September 2019 OVERVIEW Initial management of sepsis and septic shock involves consideration of: resuscitation early administration of appropriate antibiotics following blood cultures early source control judicious fluid resuscitation, avoiding excess fluids noradrenaline for refractory hypotension (septic shock) inotropes…
Fatigue and the Critical Care Doctor
Fatigue = sleep and rest deprivation that negatively impacts on performance
Open Disclosure
Open Disclosure is the process of communicating with a patient and/or their support person(s) about a patient-related incident or harm caused during the process of healthcare
Activated Protein C
Activated Protein C: endogenous human protein; recombinant glycoprotein with anti-thrombotic, profibrinolytic and anti-inflammatory properties.