Renal Disease Biomarkers
Acute kidney injury (AKI) is a common problem in the critically ill associated with increased morbidity and mortality
Category CCC
The LITFL Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care.
Renal Transplant Patient
Renal Transplant; commonest transplant; anastamosed to common iliac artery and vein in the pelvis. the ureter is plumbed into the bladder; allows ease of access for palpation and biopsy
RIFLE Criteria and AKIN Classification
AKI can be defined as an abrupt (1 to 7 days) and sustained (more than 24 hours) decrease in kidney function. The ADQI formulated the RIFLE criteria in 2004 to allow for AKI to be objectively and uniformly defined.
APACHE versus SOFA scoring systems
APACHE = Acute Physiology, Age and Chronic Health Evaluation (I-IV); SOFA = Sequential Organ Failure Assessment
ICU Scoring Systems
Scoring systems commonly used in ICU: GCS; TISS; APACHE; SAPS; MPM; POSSUM; EuroSCORE; MELD and SOFA
Multiple Organ Dysfunction Syndrome
Multiple Organ Dysfunction Syndrome (MODS) is a hypometabolic, immunodepressed state with clinical and biochemical evidence of decreased functioning of the body's organ systems that develops subsequent to an acute injury or illness.
Antimicrobial Dosing and Kill Characteristics
Dosing is different to non-critically ill patients
Different antimicrobials have different kill characteristics, which can be demonstrated on a concentration vs time graph for antibiotic activity
Paediatric Asthma
See RCH Melbourne Guidelines: Acute Asthma Asthma discharge pack Asthma devices photoboard Using a puffer and spacer to treat acute asthma
Cognitive Dispositions to Respond
Reviewed and revised 8 December 2014 OVERVIEW Cognitive Dispositions to Respond (CDRs) or cognitive biases are: “Predictable tendencies, or biases, to react to contextual clues that are largely unconscious and may contribute to flaws in reasoning; a mental state that embraces…
ILCOR Guideline Changes 2010
ILCOR = International Liaison committee on Resuscitation = conglomerate of resuscitation councils worldwide. Changes in 2010
Fluid bolus therapy
Fluid bolus therapy is widely administered to patients with undifferentiated hypotension and for patients with severe sepsis
Fluid Challenge
The fluid challenge (FC) aims at identifying patients in whom fluid administration improves haemodynamics (known as "fluid responsiveness")