Fisher’s Exact Test
Fisher's Exact Test is to compare categorical data; more complicated to perform than the Chi square test; only generally applicable in 2 x 2 contingency table
Category CCC
The LITFL Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care.
ICU Outcomes
Outcome measures are important for research and quality control; clinically meaningful outcomes measure how patients feel, function or survive, e.g. mortality, quality of life
Intention to treat analysis
Intention to treat (ITT) analysis means all patients who were enrolled and randomly allocated to treatment are included in the analysis and are analysed in the groups to which they were randomized
Meta-analysis and Systematic Review
Meta-analysis is a tool for quantitative systematic review of observational studies and controlled trials that weights available evidence based on the numbers of patients included, the effect size, and often statistical tests of agreement with other trials
Measures of Variability
Measures if variability describe the average dispersion of data around a mean; most common = range, standard deviation and the standard error of the mean
Phases of Clinical Research
Phases of clinical research are the steps taken to gather evidence to determine whether a novel intervention or treatment is safe and effective for clinical use
Propensity Score Analysis
Propensity analysis refers to statistical methods used to control for treatment selection bias in observational studies
Thoracic Trauma
Assessment of thoracic trauma requires the identification of immediately life-threatening injuries on primary survey, and delayed life threats on secondary survey.
Spinal Cord Anatomy and Syndromes
Spinal Cord Anatomy and Syndromes
Inhalation Injury
Inhalation Injury: 20% in burn patients; 60% in burns patients with central facial burns; causes a massive increase in mortality
Finger Thoracostomy
Finger Thoracostomy: Any pneumothorax in a patient undergoing positive pressure ventilation; Actual or near traumatic cardiac arrest; Shocked state with no apparent cause; Pleural drainage is not indicated in drowning or hangings unless pneumothorax is diagnosed. Remember pleural decompression will reduce the efficiency of the ACD and impedance valve
Extremity Injuries
The most important extremity injuries are those that are either life-threatening or limb-threatening in nature such as Pelvic disruption with massive hemorrhage; Severe arterial hemorrhage; and Crush syndrome