Category CCC

The LITFL Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care.

CCC Critical Care compendium 340

Phases of Clinical Research

Phases of clinical research are the steps taken to gather evidence to determine whether a novel intervention or treatment is safe and effective for clinical use

CCC Critical Care compendium 340

Thoracic Trauma

Assessment of thoracic trauma requires the identification of immediately life-threatening injuries on primary survey, and delayed life threats on secondary survey.

CCC Critical Care compendium 340

Inhalation Injury

Inhalation Injury: 20% in burn patients; 60% in burns patients with central facial burns; causes a massive increase in mortality

CCC Critical Care compendium 340

Finger Thoracostomy

Finger Thoracostomy: Any pneumothorax in a patient undergoing positive pressure ventilation; Actual or near traumatic cardiac arrest; Shocked state with no apparent cause; Pleural drainage is not indicated in drowning or hangings unless pneumothorax is diagnosed. Remember pleural decompression will reduce the efficiency of the ACD and impedance valve

CCC Critical Care compendium 340

Extremity Injuries

The most important extremity injuries are those that are either life-threatening or limb-threatening in nature such as Pelvic disruption with massive hemorrhage; Severe arterial hemorrhage; and Crush syndrome

CCC Critical Care compendium 340

Electrical Injury

OVERVIEW Definitions Flow = change in P/resistance Change in P = flow x resistance V = IR Voltage = the tendency of electrons to move through a conductive system (volts)Resistance = tendency of a material to limit flow of electrons…

CCC Critical Care compendium 340

Compartment Syndrome CCC

Musculoskeletal compartment syndrome is a limb threatening condition resulting from increased pressure within a muscular compartment, which causes compression of the nerves, muscles and vessels within the compartment.

CCC Critical Care compendium 340

Digoxin

CLASS MECHANISM OF ACTION DIRECT:inhibition of Na/K ATPase on the cell surface-> increased intracellular Na+ and increased extracellular K+-> increased intracellular Ca2+ due to Na+/Ca2+ antiporter-> calcium-medated  inotropy and increased automaticity, as well as negative dromotropy due to decreased intracellular K+ INDIRECT…