Measures of Variability
OVERVIEW
Measures of variability describe the average dispersion of data around a mean
most common = range, standard deviation and the standard error of the mean
Summary
- range
- percentiles
- standard deviation
- standard error
- confidence intervals
- z-transformation
RANGE
- smallest & largest values in a sample
PERCENTILES
- tell me what percentage of scores are less than your one.
- median = 50th percentile
- interquartile range = middle 50% of observations around the median
- to calculate percentile = (desired percentile/100) x (number of numbers + 1)
STANDARD DEVIATION (SD)
- a measure of the average spread of individual values around the sample or population mean
- calculated by squaring the differences between each value and the sample mean, summing them then dividing the result by n – 1 to give the variance
- SD = the square root of the variance
- SD important because:
- reporting the SD along with the mean, gives an indication at a glance as to whether the sample mean represents a real trend in the sample
- if the sample is randomly selected and large -> it can be assumed to be close to that of the population
- the SD is used to calculate the standard error (see below)
- any data point from a normal distribution can be described as a multiple of standard deviations from the population mean
- tables will then tell us the proportion of the distribution with values more extreme than that (z transformation)
STANDARD ERROR
- Standard error is an estimate of the spread of sample means around the population mean
- it is estimated from the data in a single sample
- it is an estimated prediction based on the number in the sample and the sample sd
SE = SD / square root of n
- thus, the variability among sample means will be increased if there is
- (a) a wide variability of individual data and
- (b) small samples
- SE used in parametric tests to quantify the difference between a sample mean & its proposed population mean, i.e. how far the two are apart in multiples of the SE (z-transformation)
- SE is used to calculate confidence intervals
CONFIDENCE INTERVALS
- CI is the range around a sample mean within which you predict the means of the sample’s population lies
- the range in which you predict the ‘true’ value lies
Calculation
- 95% of sample means should lie between 1.96 standard error of the mean above & below their sample mean
- thus, if the sample is large enough and is normally distributed as long as the sample was randomly selected then it should also represent the 95% CI for the population mean
- the population mean doesn’t fall within this range -> there is a 95% chance that the samPle is from a different population
Information provided
- an indication of the precision of the sample mean as an estimate of the population mean
- the wider the CI, the greater the imprecision, the greater the potential difference between the calculated sample mean & ‘true’ mean
Causes of wide CI’s
- small sample
- large variance within samples
CI vs P value
- p gives a probability of a specific hypothesis being right or wrong
- CI’s allow more scope for reader judgement on significance
Critical Care
Compendium
Chris is an Intensivist and ECMO specialist at The Alfred ICU, where he is Deputy Director (Education). He is a Clinical Adjunct Associate Professor at Monash University, the Lead for the Clinician Educator Incubator programme, and a CICM First Part Examiner.
He is an internationally recognised Clinician Educator with a passion for helping clinicians learn and for improving the clinical performance of individuals and collectives. He was one of the founders of the FOAM movement (Free Open-Access Medical education) has been recognised for his contributions to education with awards from ANZICS, ANZAHPE, and ACEM.
His one great achievement is being the father of three amazing children.
On Bluesky, he is @precordialthump.bsky.social and on the site that Elon has screwed up, he is @precordialthump.
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