OVERVIEW Lupus Anticoagulants -> result in acquired hypercoagulability due to poorly understood actions ? alteration of the regulation of haemostasis and endothelial cell injury ASSOCIATIONS MANAGEMENT (1) APTT (2) dilute Russell viper venom time (3) silica clotting time(4) kaolin clotting…
Isolated Elevated APTT
Haemolytic uraemic syndrome (HUS) is a clinically similar condition to TTP; in HUS (unlike TTP): renal failure > neurological symptoms
Reviewed and revised 27 October 2016 OVERVIEW Definition Haemolytic anaemia is anemia due to shortened survival of red blood cells (RBCs) in the circulation Normal RBC lifespan is about 120 days, therefore it is useful to think of hemolytic anemia…
Haematology Literature Summaries
Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by the intravascular activation of coagulation with loss of localization arising from different causes
Apheresis, Plasmapheresis and Plasma Exchange
new terms that are in vogue are trauma-induced coagulopathy (TIC) and acute traumatic coagulopathy (ATC) - not simply a 'dilutional coagulopathy' or 'consumptive coagulopathy'!
Transfusion Literature Summaries
What is the explanation for the discrepancy between the oxygen saturations on pulse oximetry and on arterial blood gas analysis in this patient?
The trauma room has turned into a blood bath. You're going to have to buy new shoes. What should you throw at the patient - the kitchen sink or Factor VII?
What are the definitions used to define "Critical Bleeding" and "Massive Transfusion"?