Description What is the actual eponymous medical sign/syndrome/repair/classification… History 1885 – Pieter Klazes Pel first described this phenomenon in Berliner klinische Wochenschrift. A 25-year-old paper maker died after a four-month illness, in which five 10-30 day episodes of fever, each with swelling of the spleen, alternated with fever-free intervals of 10-15 days. On autopsy, the spleen […]
Haematology
Jean-Baptiste Denis
Jean-Baptiste Denis (1640- 1704) was a physician and Professor of philosophy and mathematics. Blood transfusion(xenotransfusion) in 1667
Prof P.K. Pel
Pieter Klazes Pel (1852 – 1919) was a Dutch physician and professor of internal medicine.
Thomas Hodgkin
Thomas Hodgkin (1798 – 1866) was an English physician and pathologist. Eponym: Hodgkin disease (1832); Key-Hodgkin murmur (1827)
Leukodepleted Blood
RBCs used for transfusion in Australia and New Zealand are now universally leukodepleted; leukodepletion filters were previously used at the bedside
Blood Transfusion in ICU
OVERVIEW anaemia common in ICU tendency to more restrictive strategy c/o increased morbidity associated with transfusion general attempts to minimize the requirement for blood transfusion should be pursued STRATEGIES TO MINIMISE BLOOD TRANSFUSION REQUIREMENTS stopping bleeding early stop unnecessary anticoagulation and antiplatelet agents minimising venesection use blood conservation devices when sampling from arterial lines correct […]
Blood Bank and Pre-Transfusion Testing
blood products undergo a meticulous collection, preparation and testing process to minimise the risks of blood transfusion
Thrombotic Thrombocytopenic Purpura
Thrombotic Thrombocytopenic Purpura (TTP) is a rare life-threatening condition that resembles HUS, the distinction is important because TTP can be treated with plasmapheresis
Thrombocytopaenia
Definition of thrombocytopenia is a platelet count < 150 × 10E9/L most common haemostatic abnormality in ICU patients
Sickle Cell Crisis
OVERVIEW Sickle cell disease is caused by HbS haemoglobinopathy which produces rigid, distorted and dysfunctional erythrocytes called sickle cells CAUSE Types of sickle cell disease sickle cell anemia (usually homozygous SS genotype) sickle beta thalassemia sickle HbC disease PRECIPITANTS Commonly: infection dehydration hypoxia drugs (e.g. sedatives, local anaesthetics) Patients with sickle cell disease are at […]
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