Biography Born 12 April 1887, Luzern 1909-1912 Studied medicine in Zürich, Berlin, and Berne 1914 – MD, Berne 1915 – Postgraduate studies at the paediatric clinic in the Charité, Berlin 1929 – Privatdozent in paediatrics, Berne 1932 – Professor and Director…
Catecholamine excess, or 'sympathetic overload', may be harmful in critically ill patients, including those with septic shock. Catacholamine excess is associated with specific conditions such as Takotsubo cardiomyopathy
Theophylline and caffeine are the most commonly encountered methylxanthines. Theophylline = water soluble aminophylline derivative; cAMP phosphodiesterase inhibitors
Abnormal vital signs in patient's following toxic exposures can suggest underlying toxidromes. Differential diagnosis of abnormal signs
The differential diagnosis of toxicological causes of cardiac arrest are many and varied. It is useful to consider the causes in terms of mechanism.
Indications Contraindications: Choose the correct catheter Handy Hints: References and Links
Tenecteplase is a tissue plasminogen activator used as a thrombolytic medication in: Acute Ischaemic Strokes, Acute Myocardial Infarction, PE
Aubrey Otis Hampton (1900 - 1955) was an American Radiologist. Eponymously affiliated with Hampton hump and Hampton line
Malignant Hyperthermia = pharmacogenetic disease of skeletal muscle induced by exposure to certain anaesthetic agents; incidence 1:5,000 -> 1:65,000 anaesthetics (suspected); mutation in the gene coding for the ryanodine receptor
Anticholinergic Syndrome
Much of what we do in toxicology is because we think it works, not because we know it works. Clinical toxicology has traditionally been based on animal studies, case reports and case series based on clinical observation rather than clinical trials
Iron overdose can have local gastrointestinal effects as well as characteristic systemic toxicity (metabolic acidosis, liver failure, shock and multi-organ failure). Risk assessment is based on the amount of elemental iron ingested