Toxoplasmosis
Toxoplasmosis: disease caused by Toxoplasma gondii; obligatory intracellular protozoan; cat gut multiplication -> oocysts excreted in faeces -> invasion of hosts and formation of tissue cysts (retinal and brain).
Category Medical Specialty
Tuberculosis
Tuberculosis (TB) is the most important infectious cause of death worldwide and is caused by the Mycobacterium tuberculosis complex
Urosepsis
Urosepsis is a severe infection, distinguishing it from other urinary tract infections including mild pyelonephritis and accounts for ~5% of severe sepsis; whereas UTIs account for ~40% of nosocomial infections
Varicella Zoster
Varicella Zoster VZV = an alpha herpes virus; 90% of adults have evidence of infection; spread via droplet excreted from the throat of patients with chicken pox OR via contact with vesicle fluid in chicken pox or shingles.
Vibrio infection
OVERVIEW organisms: Vibrio vulnificus and other species CLINICAL FEATURES tropical environments sea water borne cut to skin -> cellulitis -> necrotizing cellulitis profound multi-organ failure RISK FACTORS raw oyster consumption liver disease iron overload INVESTIGATIONS tissue culture blood cultures MANAGEMENT…
Léon Clément Le Fort
Léon Clément Le Fort (1829 – 1893) was a French surgeon. Eponym: Wagstaffe-Le Fort fracture (1886); Le Fort Operation for uterine prolapse; Le Fort amputation; Le Fort Male Catheter; and Le Fort sound. Godfather of FOAM 'Liberté de l'enseignement'
Waterborne Diseases
Waterborne Disease: major killer of the paediatric patient in the developed world
Stenotrophomonas maltophilia
Stenotrophomonas maltophilia is an environmental global emerging Gram-negative MDRO that is most commonly associated with respiratory infections in humans
Spinal epidural abscess
Spinal epidural abscess is considered a neurosurgical emergency; morbidity and mortality is worse with delayed diagnosis, and the worse the neurological deficit at the time of surgery the worse the outcome
Carotid Endarterectomy
Carotid Endarterectomy = removal of atheromatous plaque from the ICA. Artery clamped, open, plaque stripped and then closed directly or with a Gore-Tex vein patch.
AAA Repair Patient Hot Case
GENERAL APPROACH Emergency or Elective End-organ damage Complications– brain injury– spinal cord ischaemia– ileus– MI– lower limb ischaemia– compartment syndromes– renal injury INTRODUCTION CUBICLE dialysis INFUSIONS vasoactives fluid boluses sedation analgesia transpyloric feeding: ileus, ischaemia TPN VENTILATOR mode level of…
GI Drug Absorption in Critical Illness
GI Drug Absorption in Critical Illness; multi-factorial determinants influence the bioavailability of drugs; governed by factors altering transport of substances across cell membranes (diffusion, active transport, ultrafiltration)