Moritz Roth (1839-1914) was a Swiss pathologist.
He is eponymously associated with Roth spots (1872), which he first observed in the retina of patients with septicaemia. Dr Moritz Roth contributed numerous articles to the European medical journals, along with works on medical history.
He wrote a definitive biography of Andreas Vesalius Bruxellensis (1514-1564), one of the founders of human anatomy, with 27 editions published between 1886 and 2010 in 4 languages.
- Born 25 December 1839, Basel, Switzerland
- Education at the Universities of Würzburg, Göttingen, and Berlin
- 1864 – Graduated with M.D. degree, University of Basel, Switzerland
- 1866 – Appointed privatdozent (‘adjunct professor’), University of Basel
- 1868 – Appointed privatdozent, University of Greifswald, Germany
- 1872 – Assistant Professor, University of Basel
- 1874 – Professor of pathology and pathological anatomy, University of Basel
- 1898 – Resigned
- Died 4 November 1914, Gottlieben
Roth spot (1872)
Roth spots [aka Litten sign, Litten spots ] Retinal haemorrhages with white or pale centers, associated commonly with subacute bacterial endocarditis, and immune complex mediated vasculitis.
- Roth’s original description of his eponymous sign was retinal white spots and separate scattered haemorrhages (retinal red spots) in close proximity to the optic disc in patients with septicaemia.
- Moritz Litten (1845-1907) first used the term ‘Roth spot’ in his 1876 article (published 1878) to describe the current understanding of Roth spots, when he observed retinal haemorrhages with a white centre in patients with endocarditis. Sometimes referred to as Litten sign
- Roth M. Untersuchungen über die Drüsensubstanz der Niere. 1864
- Roth M. Über Netzhautaffectionen bei Wundfiebern. I. Die embolische Panophthalmitis. Deutsche Zeitschrift für Chirurgie, 1872; 1(5): 471-484. [Roth spots]
- Roth M. Andreas Vesalius Bruxellensis. Berlin: Reimer. 1886
- Roth M. Quellen einer Vesalbiographie. Basel: Baur 1889.
- Roth M. Aus den Anfängen der Basler medicinischen Fakultät. Basel: Schweighauser. 1896
- Litten M. Uber akute maligne endokarditis und die dabei vorkommenden retinalveränderungen. Charité-Annalen 1876; III: 137-172. (published 1878)
- Singer I, Haneman FT. The Jewish Encyclopedia: a descriptive record of the history, religion, literature, and customs of the jewish people from the earliest times to the present day. Funk & Wagnalls, New York, 1906; 10: 488.
- Khawly JA, Pollock SC. Litten’s Sign (Roth’s Spots) in Bacterial Endocarditis. Arch Ophthalmol. 1994;112(5):683-684
- Lepore F. Roth’s Spots in Leukemic Retinopathy. N Engl J Med 1995; 332:335.
- Fred HL. Little black bags, ophthalmoscopy, and the Roth spot. Tex Heart Inst J. 2013;40(2):115–116.
the person behind the name