Isolated Elevated APTT
Isolated Elevated APTT
Thyroid Storm
Thyroid Storm: life threatening exacerbation of hyperthyroid state with 1 or more organ dysfunction
Pheochromocytoma
Pheochromocytoma: paraganglioma -> catecholamine producing tumours; associated with: MEN, von Hippel-Lindau syndrome, neurofibromatosis and familial paragangliomas
Myxoedema Coma
Myxoedema Coma: extreme form of hypothyroidism; high mortality
Haemolytic Uraemic Syndrome
Haemolytic uraemic syndrome (HUS) is a clinically similar condition to TTP; in HUS (unlike TTP): renal failure > neurological symptoms
Haemolytic anaemia
Reviewed and revised 27 October 2016 OVERVIEW Definition Shortened lifespan can be due to RBC destruction from: The approach to haemolytic anaemia involves: In the critically ill, always consider: PATHOGENESIS Haemolysis can occur intravascularly or extravascularly, or both Immune-mediated Non-immune…
Haematology Literature Summaries
Haematology Literature Summaries
Haematological Emergencies
almost all haematological malignancies are curable with modern treatments such as chemotherapy, radiotherapy, immunotherapy and bone marrow transplantation
Disseminated intravascular coagulation
Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by the intravascular activation of coagulation with loss of localization arising from different causes
Apheresis, Plasmapheresis and Plasma Exchange
Apheresis, Plasmapheresis and Plasma Exchange
Antiphospholipid Syndrome
antiphospholipid syndrome (APS) is diagnosed by the occurrence of thrombosis or pregnancy morbidity in combination with detectable antibodies
Acute Coagulopathy of Trauma
new terms that are in vogue are trauma-induced coagulopathy (TIC) and acute traumatic coagulopathy (ATC) - not simply a 'dilutional coagulopathy' or 'consumptive coagulopathy'!