- 2 patients
- treatment dependent on stage of pregnancy (first trimester: avoidance of teratogenicity, third trimester: prevention of pre-term labour)
- signs of severe sepsis may be masked by normal pregnancy changes
- these two patients require synchronous resuscitation, evaluation and treatment.
- Call for help early – obstetrics, anaesthesia, neonatal team
- A – intubate if indicated, may be difficult, call for help early
- B – consider NIV, avoid permissive hypercapnia c/o fetal acidosis, optimize blood flow to placenta
- C – left lateral position, fluid loading, pressors and inotropes
Early cultures and antibiotics (see below)
Evaluation and Management
-> previous pneumonia
-> volume status
-> complications: empyema, cerebritis
-> other organ involvement
-> blood cultures
-> CXR: with protection of baby
-> urinary antigens (pneumococcal and legionella)
-> nasopharyngeal swab (H1N1)
-> exclude non respiratory cause of sepsis
-> antibiotics: cefuroxime, erythromycin, oseltamivir
- avoid teratogenicity
- assessment fetal well being (CTG, U/S)
- consider LSCS if clinical deterioration
- thromboprophylaxis (high risk patient)
- ulcer prevention
- aspiration prophylaxis
- early anaesthetic consult
- early transfer to a tertiary unit
- ICU admission
- close liaison with family and teams
Chris is an Intensivist and ECMO specialist at the Alfred ICU in Melbourne. He is also a Clinical Adjunct Associate Professor at Monash University. He is a co-founder of the Australia and New Zealand Clinician Educator Network (ANZCEN) and is the Lead for the ANZCEN Clinician Educator Incubator programme. He is on the Board of Directors for the Intensive Care Foundation and is a First Part Examiner for the College of Intensive Care Medicine. He is an internationally recognised Clinician Educator with a passion for helping clinicians learn and for improving the clinical performance of individuals and collectives.
After finishing his medical degree at the University of Auckland, he continued post-graduate training in New Zealand as well as Australia’s Northern Territory, Perth and Melbourne. He has completed fellowship training in both intensive care medicine and emergency medicine, as well as post-graduate training in biochemistry, clinical toxicology, clinical epidemiology, and health professional education.
He is actively involved in in using translational simulation to improve patient care and the design of processes and systems at Alfred Health. He coordinates the Alfred ICU’s education and simulation programmes and runs the unit’s education website, INTENSIVE. He created the ‘Critically Ill Airway’ course and teaches on numerous courses around the world. He is one of the founders of the FOAM movement (Free Open-Access Medical education) and is co-creator of litfl.com, the RAGE podcast, the Resuscitology course, and the SMACC conference.
His one great achievement is being the father of three amazing children.
On Twitter, he is @precordialthump.