Precautionary Principle and the Kehoe Principle

OVERVIEW

  • The Precautionary Principle and Kehoe Principle reflect different conceptions of risk in the absence of evidence

THE KEHOE PRINCIPLE

  • The ‘Kehoe Principle’ is a commonly made misconception summarised as:

The absence of evidence of risk = Evidence of the absence of risk

  • Robert A. Kehoe was a toxicologist employed by the Ethyl Corporation in the 1920s
  • He exemplified the ‘show me the data‘ mentality in defending the safety of leaded petrol
  • His stance was based on the rationale that there was no convincing published evidence of harm to humans
  • Subsequent research demonstrating harm led to the complete removal of lead from gasoline in the United States by 1986

PRECAUTIONARY PRINCIPLE

  • This is a safer, more rational approach to think about risk in the absence of evidence:

The absence of evidence of risk = a possibility of risk until proven otherwise

  • use of the precautionary principle puts the burden of proof on those that claim an action does not cause harm
  • however, it is not a useful decision-making principle on it’s own — any course of action needs to weight the benefits and risks — and all claims (whether for benefit or risk) carry a burden of proof

References and Links

Journal articles

  • Nriagu JO. Clair Patterson and Robert Kehoe’s paradigm of “show me the data” on environmental lead poisoning. Environ Res. 1998 Aug;78(2):71-8. PMID: 9719610.
  • Peterson M. The precautionary principle should not be used as a basis for decision-making. Talking point on the precautionary principle. EMBO Rep. 2007 Apr;8(4):305-8. PMC1852769.

CCC 700 6

Critical Care

Compendium

Chris is an Intensivist and ECMO specialist at The Alfred ICU, where he is Deputy Director (Education). He is a Clinical Adjunct Associate Professor at Monash University, the Lead for the  Clinician Educator Incubator programme, and a CICM First Part Examiner.

He is an internationally recognised Clinician Educator with a passion for helping clinicians learn and for improving the clinical performance of individuals and collectives. He was one of the founders of the FOAM movement (Free Open-Access Medical education) has been recognised for his contributions to education with awards from ANZICS, ANZAHPE, and ACEM.

His one great achievement is being the father of three amazing children.

On Bluesky, he is @precordialthump.bsky.social and on the site that Elon has screwed up, he is @precordialthump.

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