Respiratory Failure Hot Case

GENERAL APPROACH

Respiratory failure in general

  • Brain
  • Cough
  • Nerves
  • NMJ
  • Respiratory Muscles
  • Pleura
  • Airways (large and small)
  • Parenchymal
  • Chest wall
  • Ventilator asynchrony
  • Cardiac failure
  • Abdominal distension/failure

Respiratory Failure in the Haematology/Oncology patient

  • determine phase of illness (new diagnosis, post chemo, post BMT – acute, early, late)
  • determine level of immunosuppression (neutropaenia, pancytopaenia)

Causes in the Haematology/Oncology patient

  • infection
    – bacterial: multiple causes
    – viral: CMV, HSV, VSV
    – fungal: PJP, aspergillus, candida
    – protozoa: toxoplasmosis
  • engraftment
  • BOOP
  • diffuse alveolar haemorrhage
  • idiopathic pulmonary syndrome
  • cardiac failure

INTRODUCTION

CUBICLE

  • inhalers
  • ventilators
  • sputum
  • isolation (MDRO)

INFUSIONS

  • bronchodilators
  • antibiotics (MDRO)
  • heavy sedation + paralysis
  • IVIG (GB, MG, vasculitis)

VENTILATOR

  • type of ventilation (NIV, invasive, spontaneous breaths, controlled, oscillation, ECMO)
  • assess ventilation strategy (ARDS, bronchospasm, selective ventilation)
  • level of support
  • level of oxygenation
  • disease specific questions (ARDS: plateau pressure, bronchospasm: dynamic hyperinflation, intrinsic PEEP)

MONITOR

  • temperature
  • ETCO2 (waveform, value, remember to compare to PaCO2 for dead space assessment)
  • CVP (number, waveform)
  • arterial trace (pressure, swing, pulsus paradoxus)

EQUIPMENT

  • intercostals drains (number, bubbling, drainage)
  • PAC (ask for recent numbers)
  • PICCO (ask for recent numbers)
  • iNO
  • inhaled prostacyclin
  • IABP

QUESTION SPECIFIC EXAMINATION

  • hands/arms -> head -> chest -> abdo -> legs/feet -> back

-> cardiovascular
-> respiratory
-> abdominal (distension)

neurological

-> paralysed
-> quick examination
-> unconscious
-> conscious

RELEVANT INVESTIGATIONS

Bedside

  • ABG

Laboratory

  • microbiology: sputum, blood cultures

Imaging

  • CT chest

OPENING STATEMENT

  • = “Multi-factorial” and list headings of causes -> clinical signs associated with list

CCC 700 6

Critical Care

Compendium

Chris is an Intensivist and ECMO specialist at The Alfred ICU, where he is Deputy Director (Education). He is a Clinical Adjunct Associate Professor at Monash University, the Lead for the  Clinician Educator Incubator programme, and a CICM First Part Examiner.

He is an internationally recognised Clinician Educator with a passion for helping clinicians learn and for improving the clinical performance of individuals and collectives. He was one of the founders of the FOAM movement (Free Open-Access Medical education) has been recognised for his contributions to education with awards from ANZICS, ANZAHPE, and ACEM.

His one great achievement is being the father of three amazing children.

On Bluesky, he is @precordialthump.bsky.social and on the site that Elon has screwed up, he is @precordialthump.

| INTENSIVE | RAGE | Resuscitology | SMACC

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