Submassive PE on EMCrit
Back in RAGE Session Two we discussed ‘Thrombolysis for Submassive Pulmonary Embolus‘. This was actually just before the PEITHO trial was published, though we were able to anticipate many of the findings thanks to the wonders of the web.
A great follow up to our discussion is EMCrit Podcast 128 – Pulmonary Embolism Treatment Options and the PEAC Team with Oren Friedman. This discussion reiterates many of the conclusions the RAGE team came to, with additional discussions about catheter-directed thrombolysis and reduced dose thrombolysis.
Meanwhile, the NEJM has just published correspondence in response to the PEITHO trial -it includes a comment about half-dose thrombolysis by Rory Spiegel, myself and Ryan Radecki.
References
- Weingart S. Pulmonary Embolism Treatment Options and the PEAC Team with Oren Friedman. EMcrit 2014.
- Spiegel R, Nickson C, Radecki R. Fibrinolysis for Intermediate-Risk Pulmonary Embolism. NEJM 2014
Thanks again for listening to the RAGE!
Chris is an Intensivist and ECMO specialist at The Alfred ICU, where he is Deputy Director (Education). He is a Clinical Adjunct Associate Professor at Monash University, the Lead for the Clinician Educator Incubator programme, and a CICM First Part Examiner.
He is an internationally recognised Clinician Educator with a passion for helping clinicians learn and for improving the clinical performance of individuals and collectives. He was one of the founders of the FOAM movement (Free Open-Access Medical education) has been recognised for his contributions to education with awards from ANZICS, ANZAHPE, and ACEM.
His one great achievement is being the father of three amazing children.
On Bluesky, he is @precordialthump.bsky.social and on the site that Elon has screwed up, he is @precordialthump.
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