The electrolyte composition of Hartmann’s solution (1932) is similar to Ringer's solution (1882) first formulated to maintain cellular function
Sydney Ringer (1835-1910) British clinician, physiologist and pharmacologist. Ringer's 'discovery' of his solution (Ringer's solution) arose after his lab assistant mistakenly substituted tap water from the New River Water Co. for distilled water whilst experimenting on a frogs heart.
Alexis Frank Hartmann (1898-1964) American pediatrician and clinical biochemist. Developed Lactated Ringer’s solution (Hartmann’s Solution)
ACEM Primary Pharmacology of Intravenous Fluids: the Pharmacokinetics; Pharmacodynamics; Clinical uses; Adverse effects