
Hypertonic Saline vs Mannitol
Hypertonic Saline vs Mannitol - The Answer? The perennial debate of which osmotic agent to use to reduce elevated ICP still rages on.

Hypertonic Saline vs Mannitol - The Answer? The perennial debate of which osmotic agent to use to reduce elevated ICP still rages on.

ACEM Primary Pharmacology of Mannitol: the Pharmacokinetics; Pharmacodynamics; Clinical uses; Adverse effects

Mannitol: osmotic diuretic; increases the osmolarity of the glomerular filtrate -> increasing urinary volume; decreases CSF volume and pressure