Tag N-acetylcysteine
Toxicology Library Tox Tutes 340

Paracetamol Update

Paracetamol / Acetaminophen Update. Dr Angela Chiew – Australian Clinical Toxicologist and Emergency Staff Specialist


N-acetylcysteine (NAC) is the most widely used sulfhydryl donor in the treatment of paracetamol poisoning. Standard therapy consists of a series of three infusions given over 20 hours.
CCC Critical Care compendium 340


N-acetylcysteine (NAC): glutathione supplementation ? protects the liver by maintaining and restoring glutathione levels or by acting as an alternate substrate for conjugation with -> detoxification of reactive metabolites.