Part One is a fantastic new FOAM resource created by Jake Barlow for critical care trainees preparing for basic science examinations, specifically the CICM and ANZCA first part examinations held in Australasia.
Basic Science
Mannitol
Mannitol: osmotic diuretic; increases the osmolarity of the glomerular filtrate -> increasing urinary volume; decreases CSF volume and pressure
Factor VIIa
Tissue factor + VIIa + platelets -> platelet aggregation -> production of platelet-fibrin matrix -> haemostasis; used in massive transfusion senario’s to attempt to control intractable haemorrhage
Oxygen
Oxygen: gaseous inorganic element; essential role in oxidative phosphorylation resulting in energy production in the form of ATP
Activated Protein C
Activated Protein C: endogenous human protein; recombinant glycoprotein with anti-thrombotic, profibrinolytic and anti-inflammatory properties.
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