Part One is a fantastic new FOAM resource created by Jake Barlow for critical care trainees preparing for basic science examinations, specifically the CICM and ANZCA first part examinations held in Australasia.
Mannitol: osmotic diuretic; increases the osmolarity of the glomerular filtrate -> increasing urinary volume; decreases CSF volume and pressure
Tissue factor + VIIa + platelets -> platelet aggregation -> production of platelet-fibrin matrix -> haemostasis; used in massive transfusion senario’s to attempt to control intractable haemorrhage
Oxygen: gaseous inorganic element; essential role in oxidative phosphorylation resulting in energy production in the form of ATP
Activated Protein C: endogenous human protein; recombinant glycoprotein with anti-thrombotic, profibrinolytic and anti-inflammatory properties.