Lung Transplant
Can have one or both lungs transplanted depending on disease process. Single lung transplants only suitable for non-infective conditions that will not go on to damage new lung, with no cardiac disease
Category CCC
The LITFL Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care.
Negative Pressure Pulmonary Oedema
Negative pressure pulmonary edema (NPPE) is a form of noncardiogenic pulmonary edema (PE) that results from the generation of high negative intrathoracic pressure (NIP) needed to overcome upper airway obstruction
Oxidative Stress in Critical Illness
Oxidative stress is refers an imbalance between production of reactive oxygen species and the protection of antioxidants, due to the accumulation of free radicals and/or the inability of antioxidants to counter their accumulation or effects.
Intensive Care Outcomes
Appropriate outcome measures is vitally important in ICU research: e.g. ICU mortality; hospital mortality; 90 day mortality; 1 year functional outcome
Human Factors
Human failures rather than technical failures are the greatest threat to complex and potentially hazardous systems such as healthcare systems.
Community Acquired Pneumonia
Community Acquired Pneumonia: Streptococcus pneumonia (most common organism); other causes: Mycoplasma pneumoniae, Chlamydophila pneumoniae and Legionella, Haemophilus influenzae (in COPD)
Liver Function Tests
Liver Function Test Analysis including Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT), Alkaline Phosphatase (ALP) Lactate Dehydrogenase (LDH), Gamma Glutamyl Transferase (GGT)
Hypochloraemia
Hypochloraemia (<95) (Usually associated with sodium losses)
Oxygen
Oxygen: gaseous inorganic element; essential role in oxidative phosphorylation resulting in energy production in the form of ATP
Paediatric Formulae
Paediatric Formulae
Corrosive Ingestion
Corrosive ingestion may be life-threatening due to airway compromise or GI perforation, or due to agent-specific systemic toxicity.
Cocaine-related Chest Pain
Cocaine is a recreational drug with sympathomimetic effects in additional to being a sodium channel blocker. Cocaine can induce acute coronary syndromes through vasoconstriction, atheroma rupture and/ or dissection