
Toxic Alcohol Ingestion
Highlights and pearls on toxic alcohol ingestion from the EBMedicine article, "Toxic Alcohols: Not Always A Clear-Cut Diagnosis"
The LITFL Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care.

Highlights and pearls on toxic alcohol ingestion from the EBMedicine article, "Toxic Alcohols: Not Always A Clear-Cut Diagnosis"

Tricyclic Antidepressants (TCA) are weak bases (pKa 8.5) that can cause life-threatening sodium channel toxicity

Citrate toxicity is primarily a result of hypocalcaemia and metabolic effects of excess citrate

Spider envenoming: In Australia the only two spiders of real importance = Funnel-web and the Red-Back; only these two can cause death or severe systemic illness

Severe toxicity from mushrooms is rare in humans; most symptomatic presentations are a self-limiting gastroenteritis requiring supportive care only; lethal hepatotoxicity from Amanita mushrooms must be excluded

Ciguatera Poisoning: A bizarre poisoning syndrome with acute and sometimes severe neurological and gastrointestinal symptoms caused by eating tropical reef fish that have accumulated ciguatoxin from the dinoflagellate Gambierdiscus toxicus; most common cause of fish poisoning worldwide.

Reviewed and revised 5/5/12 LUNG TRANSPLANT right ventricular failure hyperacute rejection bilateral infiltrates: hyperacute rejection, LVF, aspiration, fluid overload immunosuppression: steroids, calcineurin antagonists, anti-proliferatives anastamosis breakdown: air leak PAC care iNO weaning extubate early bleeding HEPATIC TRANSPLANT transplant characteristics: alive/deceased…

Transplant patients are treated with immunosuppressants to prevent rejection, which makes them susceptible to infection; risk of infection depends on epidemiological factors (determines exposure) and overall state of immunosuppression (determines susceptibility)

Intra-Aortic Balloon Pump (IABP) or intra-aortic counterpulsation device the balloon is inflated during diastole to increase coronary perfusion and then deflated during systole to decrease afterload

Nosocomial or hospital-acquired pneumonia (HAP) is defined as pneumonia that is not incubating at the time of admission to hospital and develops in a patient hospitalised for >48 hours.

Medical reversal is the phenomenon of a new superior trial arising that contradicts current clinical practice. Many claims that specific treatments have a benefit have turned out not to be true.

Pediatric Anaphylaxis overview