Diabetic Ketoacidosis
Diabetic Ketoacidosis (DKA) potentially life-threatening complication of diabetes mellitus resulting from the consequences of insulin deficiency
Diabetic Ketoacidosis (DKA) potentially life-threatening complication of diabetes mellitus resulting from the consequences of insulin deficiency
Thyroid Storm: life threatening exacerbation of hyperthyroid state with 1 or more organ dysfunction
Myxoedema Coma: extreme form of hypothyroidism; high mortality
Alcoholic Ketoacidosis: rare; small proportion of chronic ethanol abusers; relatively benign if patients given IV dextrose and fluids; unclear aetiology
Adrenal insufficiency: primary, secondary and tertiary + acute/chronic
Glucose Control Literature Summaries
Stress Induced Hyperglycaemia (SIH) is transient hyperglycaemia associated with acute illness
resolves with resolution of the underlying critical illness
John Dalrymple (1803-1852) English surgeon and ophthalmologist. Dalrymple sign (1952) relating to Graves disease; dissection and histology of first case of multiple myeloma with Bence Jones (1846)
Karl Stellwag von Carion (1823 – 1904) was an Austrian ophthalmologist. Eponym: Stellwag Sign (1869) in Graves orbitopathy
Dalrymple sign: Widened palpebral tissue (lid retraction) or lid spasm seen in thyrotoxicosis (Graves disease) by John Dalrymple (1852)
von Graefe sign (lid lag sign): Failure of the upper lid to follow a downward movement of the eyeball when the patient changes his or her vision from looking up to looking down. Typically associated with hyperthyroidism and exophthalmos
Stellwag Sign: decreased, incomplete or infrequent blinking in patients with exophthalmic goitre (Graves-Basedow disease). Stellwag sign may also seen in progressive supranuclear palsy, and in dysthyroid eye disease