Category Haematology
CCC Critical Care compendium 340

Storage Lesions

Storage lesions are the adverse effects associated with the storage of blood; begins after about 2 weeks of storage and progresses with duration of storage ('RBC age')

CCC Critical Care compendium 340

Tumour Lysis Syndrome

Tumour Lysis Syndrome: oncological emergency due to turnover of high cell mass malignancies resulting in severe metabolic derangement

CCC Critical Care compendium 340

von Willebrand Disease

von Willebrand Disease: commonest inherited coagulation disorder (autosomal dominant); protein involved in (1) platelet adhesion and (2) carriage of factor VIII; leads to: factor VIII deficiency, abnormal platelet adhesiveness and abnormal vascular endothelium

CCC Critical Care compendium 340

VTE Prophylaxis

Venous thromboembolism (VTE) may contribute to up to 12% of deaths in ICU and is the No.1 preventable cause of hospital death; asymptomatic events range from 10-80% in various medical and surgical groups

CCC Critical Care compendium 340

Porphyria

OVERVIEW Porphyria = group of disorders where patients have a inability to synthesis Hb resulting in an accumulation of precursors oxidised to porphyrins hepatic and erythropoietic varieties 3 hepatic forms that effect are affected by anaesthesia (1) AIP – acute…