
Central Diabetes Insipidus
Diabetes insipidus (DI) is a condition caused by loss of the effect of antidiuretic hormone on the collecting ducts of the kidneys, resulting in loss of free water.

Diabetes insipidus (DI) is a condition caused by loss of the effect of antidiuretic hormone on the collecting ducts of the kidneys, resulting in loss of free water.

A 'volume-targeted' approach to the management of TBI developed by a Swedish group (not ABBA), based on physiological volume regulation of the intracranial compartments. The Lund concept contradicts the prevailing strategem of titrating CPP to match ICP in TBI

Temperature and TBI. Induced hypothermia has been used for years to reduced cerebral metabolic rate; manipulation of temperature has been shown to effect certain types of brain injury (therapeutic hypothermia in out-of-hospital cardiac arrest).

polyuria following TBI is common; multiple causes, some of which imply a poor prognosis. Goal is to identify and treat the cause and any complications

Brain impact apneoa is an under-appreciated cause of morbidity and mortality in traumatic brain injury (TBI)

Limitations of CT head scan in Traumatic Brain Injury (TBI)

Cerebral Perfusion Pressure (CPP) in Traumatic brain injury (TBI). Cerebral Perfusion Pressure (CPP) = MAP – ICP or CVP (whichever is highest)

External Ventricular Drain (EVD): ICP monitor than allows CSF drainage; measurement and treatment of raised ICP

Base of Skull Fracture: fracture involving the floor of the cranial vault

Increased Intracranial Pressure in TBI; normal ICP 7-15mmHg
sustained increases > 20mmHg is associated with ischaemic brain injury

Extradural ICP monitor: ICP monitoring; catheter inserted though a burr hole but does not penetrate the dura

Codman ICP Monitor: intracranial pressure monitor (aka 'BOLT')