
Leukodepleted Blood
RBCs used for transfusion in Australia and New Zealand are now universally leukodepleted; leukodepletion filters were previously used at the bedside

RBCs used for transfusion in Australia and New Zealand are now universally leukodepleted; leukodepletion filters were previously used at the bedside

OVERVIEW anaemia common in ICU tendency to more restrictive strategy c/o increased morbidity associated with transfusion general attempts to minimize the requirement for blood transfusion should be pursued STRATEGIES TO MINIMISE BLOOD TRANSFUSION REQUIREMENTS stopping bleeding early stop unnecessary anticoagulation…

blood products undergo a meticulous collection, preparation and testing process to minimise the risks of blood transfusion

Thrombotic Thrombocytopenic Purpura (TTP) is a rare life-threatening condition that resembles HUS, the distinction is important because TTP can be treated with plasmapheresis

Definition of thrombocytopenia is a platelet count < 150 × 10E9/L most common haemostatic abnormality in ICU patients

OVERVIEW Sickle cell disease is caused by HbS haemoglobinopathy which produces rigid, distorted and dysfunctional erythrocytes called sickle cells CAUSE Types of sickle cell disease sickle cell anemia (usually homozygous SS genotype) sickle beta thalassemia sickle HbC disease PRECIPITANTS Commonly:…

Polycythaemia = elevated Hb concentration from either increased RBC mass or decreased plasma volume

Massive Blood Loss

Heparin Induced Thrombotic Thrombocytopaenia Syndrome (HITTS or HIT)

Discrepancies between NIBP and Arterial Pressure

Blood Product Compatibility

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