Glucagon Therapy
Agonist at glucagon-specific Gs-protein coupled receptor, activates adenylyl cyclase resulting in increased [cAMP]i
Category Medical Specialty
Calcium Channel Blocker Toxicity
Severe calcium channel blocker toxicity is highly lethal, as a result of cardiovascular collapse. Good outcomes can be achieved through aggressive treatment and provision of circulatory support
Exophthalmos DDx
Exophthalmos is abnormal protrusion of the eyeball or eyeballs. Differential diagnosis
Shigeo Satomura
Shigeo Satomura (1919 - 1960) was a Japanese scientist. Designed and developed the Doppler Cardiograph, blood-rheograph and trasncutaneous flowmeter
Damage Control Resuscitation
Damage control resuscitation (DCR) is a systematic approach to the management of the trauma patient with severe injuries that starts in the emergency room and continues through the operating room and the intensive care unit (ICU). DCR involves haemostatic resuscitation, permissive hypotension (where appropriate) and damage control surgery
Major Haemorrhage in Trauma
Major Haemorrhage in Trauma
Digital Rectal Exam (DRE) in Trauma
Traditional ATLS teaching was that a digital rectal exam (DRE) is mandatory in trauma patients: “a finger or tube in every orifice”. This is no longer the case.
Kidney trauma
Most genitourinary injuries are not immediately life-threatening. Renal pedicle injury can lead to life-threatening hemorrhage and renal ischemia
Spleen trauma
Splenic trauma may result from blunt or penetrating abdominal injury. The spleen is the most commonly injured organ in blunt abdominal trauma
Diaphragm injury
Diaphragmatic injury can be a challenging diagnosis and is missed on imaging about 50% of the time. Comprises 0.8 to 8% of all closed blunt trauma and penetrating trauma case combined
Pelvic Trauma
Pelvic fractures are important in critical care because they are associated with: High energy mechanisms; Major haemorrhage; Other major injuries; and High morbidity and mortality
Liver trauma
Liver trauma may result from blunt or penetrating abdominal injury. The liver is the most commonly injured organ in penetrating abdominal trauma