Category Medical Specialty
Eduard Glanzmann (1887-1959) 340

Eduard Glanzmann

Biography Medical Eponyms Glanzmann thrombastenia (1918) autosomal recessive bleeding disorder characterized by deficient or dysfunctional glycoprotein (GP) IIb/IIIa complexes. In the absence of glycoprotein IIb/IIIa receptor (aka the fibrinogen receptor), platelets do not stick to each other at the site of…

CCC Critical Care compendium 340

Theophylline toxicity

Theophylline and caffeine are the most commonly encountered methylxanthines. Theophylline = water soluble aminophylline derivative; cAMP phosphodiesterase inhibitors

CCC Critical Care compendium 340

Evidence-based Toxicology

Much of what we do in toxicology is because we think it works, not because we know it works. Clinical toxicology has traditionally been based on animal studies, case reports and case series based on clinical observation rather than clinical trials

CCC Critical Care compendium 340

Iron Overdose

Iron overdose can have local gastrointestinal effects as well as characteristic systemic toxicity (metabolic acidosis, liver failure, shock and multi-organ failure). Risk assessment is based on the amount of elemental iron ingested