Haematological Toxicity of Chemotherapy
OVERVIEW
- Anaemia
- Thrombocytopaenia
- Marrow hypoplasia
- Thrombotic Microangiopathy
- Haemostasis Disorders
- Induced Leukaemia
- Impaired Cell-mediated Immunity
CAUSES
Anaemia
- methotrexate
- 5-FU
- cytarabine
- 6-mercaptopurine
Thrombocytopaenia
- nitrosoureas
Marrow Hypoplasia
- nitrosoureas
- anthracyclines
- busulfan
Thrombotic Microangiopathy
- gemcitabine
- mitomycin
Haemostasis Disorders
- L-asparaginase
Induced Leukaemia
- alkylating agents
- nitrosoureas
- etoposides
- methotrexate
- anthracyclines
Impaired Cell-mediated Immunity
- 2-CdA (cladnbine, leustatin)
- fludarabine
- pentostatin
- anti-CD52 (alemtuzumab)
- campath
Critical Care
Compendium
Chris is an Intensivist and ECMO specialist at The Alfred ICU, where he is Deputy Director (Education). He is a Clinical Adjunct Associate Professor at Monash University, the Lead for the Clinician Educator Incubator programme, and a CICM First Part Examiner.
He is an internationally recognised Clinician Educator with a passion for helping clinicians learn and for improving the clinical performance of individuals and collectives. He was one of the founders of the FOAM movement (Free Open-Access Medical education) has been recognised for his contributions to education with awards from ANZICS, ANZAHPE, and ACEM.
His one great achievement is being the father of three amazing children.
On Bluesky, he is @precordialthump.bsky.social and on the site that Elon has screwed up, he is @precordialthump.
| INTENSIVE | RAGE | Resuscitology | SMACC
