Hans Chiari

Hans Chiari (1851 – 1916)

Hans Chiari (1851-1916) was an Austrian pathologist.

He made important contributions in endocrinology, cardiology and neurology and became known for his teaching skills as a Professor in Prague.

Eponymously affiliated with the Chiari malformations; Type II Chiari malformation (Arnold–Chiari malformation) and Budd–Chiari syndrome .


Biography

  • Born 4 September 1851 Vienna, Austria, into a family of physicians.
  • Studied medicine in Vienna and worked as an assistant at the Vienna Institute of Pathology
  • Graduated 1875
  • Appointed Professor Extraordinarius at the German University in Prague, 1882
  • Died 6 May 1916 Strassburg following a throat infection

Medical Eponyms

Budd–Chiari syndrome (1899)

Hepatic venous outflow obstruction causing portal hypertension.

Whilst working as a pathologist in Prague, Chiari described three patients with hepatic vein thrombosis, together with a review of the literature including another seven patients. Chiari advanced Budd’s early description clinical and pathological correlations terming the condition ‘phlebitis obliterans’. Pathologically, the livers appeared to be congested, atrophic, and diffusely necrotic, with congestion of the spleno-portal circulation and large volume ascites.

Arnold–Chiari malformation (1891, 1894, 1896) – descent of the cerebellar tonsils and vermis, medulla and pons, with associated elongation and displacement of the fourth ventricle. Frequently occurs with hydrocephalus and also associate with myelomeningocele. Chiari credited others in his writing regarding the type 2 malformation – namely John Cleland and Julius Arnold, the former of whom had briefly described similar pot-mortem findings in a child in 1883.

Chiari malformations – abnormalities of the brain stem and cerebellum identified by Chiari on post-mortems. Type 1 (1891) – peg-like elongation of the cerebellar tonsils into the spinal canal through the foramen magnum; Type 2 aka Arnold Chiari malformation and Type 3 and 4.

Chiari network – mobile net-like connections between the valve of the coronary sinus and the valve of the inferior vena cava. An anatomical variant, usually of no clinical significance.


Major Publications


References


eponymictionary CTA

eponym

the person behind the name

Emergency physician MA (Oxon) MBChB (Edin) FACEM FFSEM with a passion for rugby; medical history; medical education; and informatics. Asynchronous learning #FOAMed evangelist. Co-founder and CTO of Life in the Fast lane | Eponyms | Books | vocortex |

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