
Fulminant Hepatic Failure
Fulminant Hepatic Failure = rapid onset of encephalopathy in conjunction with hepatic synthetic failure.

Fulminant Hepatic Failure = rapid onset of encephalopathy in conjunction with hepatic synthetic failure.

Local Anaesthetic Toxicity-> sodium channel blockade -> arrhythmias and neurotoxicity

Reviewed and revised 14 September 2014 OVERVIEW Methaemoglobinaemia is the state of excessive methaemoglobin in the blood CAUSES Congenital Acquired (toxin/drugs) CLINICAL FEATURES INVESTIGATIONS MANAGEMENT Resuscitation Specific therapy Supportive care and monitoring REASONS FOR FAILURE OF METHYLENE BLUE Consider the…

True sympatholytic agents (e.g. alpha-blockers like phentolamine, and vasodilatory agents such as GTN, SNP, etc)≥ Also beta-blocker; ca2+ blocker;
clonidine; digoxin

Theophylline and caffeine are the most commonly encountered methylxanthines. Theophylline = water soluble aminophylline derivative; cAMP phosphodiesterase inhibitors

Cause Central (Failed ADH secretion) Nephrogenic (No response to ADH) (Failed concentrating ability) Drugs References and Links

High airway pressures in the intubated patient can signify the presence of a life-threatening emergency. The underlying cause is either with the 'man or the machine' (patient versus equipment). A structured approach to this problem is essential.

Haemoptysis is the symptom of coughing up blood. Massive haemoptysis has no generally accepted definition. Suggested volumes range from 100 mL to more than 1000 mL. A more relevant definition of massive haemoptysis is the volume that is life threatening by virtue of airway obstruction or blood loss (anatomical dead space is only 100-200 mL)

Honeycomb lung differential diagnosis

Increased interstitial markings seen on chest x-ray may also be referred to as a fine reticular pattern

Causes of pulmonary fibrosis can be divided into those that affect the upper lobes and those predominantly affecting the lower lobes

Abnormal vital signs in patient's following toxic exposures can suggest underlying toxidromes. Differential diagnosis of abnormal signs