Róbert Bárány (1876 – 1936) was an Austro-Hungarian otologist.
1914 Nobel Prize in Physiology and Medicine for his “work on the physiology and pathology of the vestibular apparatus.”
Bárány built on theories of Flourens, Purkinje, Ewald. Mach, Retzius, Breuer and others, to clarify the physiology and pathology of human vestibular apparatus. Bárány’s main contribution was the clinical application of these experimental data to humans, which led to the development of methods of investigating the human equilibrium system.
- Born 22 April 1876. From a Hungarian family, born in Vienna, Austria
- 1900 – Completed medical studies, Vienna University
- 1903 – Demonstrator at the Otological Clinic under Ádám Politzer (1835 – 1920)
- 1913 – Appointed Professor Extraordinarius
- 1914 – Surgeon in the Austrian army. Volunteered for military service to test his ideas on the treatment of brain wounds. Captured, and detained as a Russian prisoner of war in the fortress of Przemysl. Whilst imprisoned he was nominated for the Nobel Prize in Physiology and Medicine for his “work on the physiology and pathology of the vestibular apparatus.” Prince Carl of Sweden persuaded the Czar to release him and he received his prize in Sweden in 1915.
- 1916 – Released from prisoner-of-war camp and collected his 1914 Nobel Prize. During his trip to Sweden Bárány was invited to take the chair of otology at the University of Uppsala
- 1917 – Emigrated to Sweden; Privatdozent and titular professor, University of Uppsala
- 1926 – Professor ordinarius, University of Uppsala
- Died 8 April 1936, Uppsala, Sweden
Bárány bogengänge ohr (1907)
Stellung der Hände, welche schematisch die Stellung der drei Bogengänge der rechten Seite zueinander angibt.
a. Ampulle des horizontalen Bogenganges, b. Ampulle des vorderen vertikalen Bogenganges, c. Ampulle des hinteren vertikalen Bogenganges, d. die gemeinsame Mündung beider Vertikalkanäle, e. die Kuppe des horizontalen Bogenganges, f. die Kuppe des vorderen vertikalen Bogenganges, g. die Kuppe des hinteren vertikalen
Position of the hands to show the relative position of the three semicircular canals (right side)
a. Ampullae of horizontal semicircular canal, b. Ampullae of anterior vertical semicircular canal, c. Ampullae of posterior vertical semicircular canal, d. the union of two vertical canals, e, f, g. Arches of horizontal (e), anterior vertical (f) and posterior vertical (g) canals respectively
Bárány chair (1907)
A rotating chair used by Bárány (1907) whilst researching the role of the inner ear in the sense of balance. In his 1910 paper he summarises the use of this rotating chair when studying rotational-induced nystagmus. A modern version of the Bárány chair is still used today, predominantly to in aerospace training to teach pilots about spatial disorientation. Bárány used the device in research into the role of the inner ear in the sense of balance.
Bei der klinischen Untersuchung des Drehnystagmus mußte ich mich, da mir bisher eine Drehscheibe nicht zur Verfügung stand, mit der Beobachtung des Nachnystagmus beim Anhalten nach Drehung begnügen. Ich bediente mich bei meinen Untersuchungen des in Fig. 7 abgebildeten Drehstuhles. Derselbe besitzt ein Gewinde ohne Ende. Der Patient nimmt auf dem Drehstuhle Platz, der Arzt ergreift die senkrecht stehende, an der Rückenlehne befestigte Stange und setzt den Drehstuhl in Bewegung. Die Geschwindigkeit der Drehung soll eine gleichmäßige sein und bei einiger Übung gelingt es auch, stets mit derselben Geschwindigkeit zu drehen. Mit der Stoppuhr gemessen betrug die Zeit für 10 Drehungen bei meinen Untersuchungen in der Regel 20 — 22 Sekunden. Ich habe mich in der großen Mehrzahl der Fälle auf die Untersuchung des horizontalen und rotatorischen Nachnystagmus nach 10 maliger Drehung beschränkt.
During the clinical examination of vertigo, since I had not previously had a turntable, I had to be content with observing the nystagmus elicited by movement. I used the swivel chair shown in Fig. 7 for my examinations. It has an endless thread. The patient takes a seat on the swivel chair, the doctor grabs the vertical bar attached to the backrest and sets the swivel chair in motion. The speed of the rotation should be even and with some practice you can always turn at the same speed. Measured with the stopwatch, the time for 10 rotations in my examinations was usually 20-22 seconds. In the vast majority of cases, I limited myself to examining the horizontal and rotational post-nystagmus after 10 rotations.
Bárány past pointing test (1906)
Assesses for imbalance in the output of the peripheral vestibular system, indicating defective functioning of the vestibular nerve or cerebellar dysfunction.
Procedure: patient is instructed to extend the arms and place the index finger of one hand on the index finger of the examiner or a static target. Eyes are then closed and arms raised above head (or lowered to knees) whilst still extended, then quickly returned to the perceived starting position.
In a normal exam the patient can easily return the finger to starting position. In an abnormal exam the patient will deviate from the starting position in the direction of their nystagmus due to a compensatory vestibulospinal reflex elicited in order to maintain position.
Bárány caloric test (1906)
A test of the functioning of the vestibular system using the phenomenon that when the auditory canal is irrigated with warm, or cold, water vertigo and nystagmus ensue.
Bárány was the first to recognise and understand the mechanism behind this; irrigation of the auditory canal with warm water warms the endolymphatic fluid in the horizontal semicircular canal due to its physical proximity. As the endolymphatic fluid is warmed it results in a decrease in the specific gravity and a tendency to rise. This forms a convection flow within the semicircular canal which activates the inner ear’s motion sensors resulting in the perception of vertigo and resultant nystagmus. A reverse flow will occur when irrigated with cold water, resulting in nystagmus in the opposite direction.
Like all good medical discoveries, Bárány discovered this by chance, A patient whose ears he was syringing said to him:
Doctor, I only get giddy when the water is not warm enough. When I do my own ears at home and use warm enough water I never get giddy.” I then called the nurse and asked her to get me warmer water for the syringe. She maintained that it was already warm enough. I replied that if the patient found it too cold we should conform to his wish. The next time she brought me very hot water in the bowl. When I syringed the patient’s ear he shouted: “But Doctor, this water is much too hot and now I am giddy again.” I quickly observed his eyes and noticed that the nystagmus was in an exactly opposite direction from the previous one when cold water had been used. It came to me then in a flash that obviously the temperature of the water was responsible for the nystagmus.
The caloric test is still used by neuroscientists and neuro-otologists today. The fact the test can be performed without the subject having to move their head allows for isolated assessment of unilateral vestibular apparatus and proves useful in neuroimaging such as functional MRI that require the subject to be immobile.
- The Bárány Society: Founded in 1960 by Dr. C.S. Hallpike and Professor C.O. Nylén, the Bárány Society is an international interdisciplinary society that facilitates contact between scientists and clinicians involved in vestibular research.
- Bárány’s alarm apparatus (1908): A noise-producing apparatus that is placed in one ear to eliminate hearing in this ear while the other ear is being investigated.
- Bárány R. Untersuchungen über den vom Vestibularapparat des Ohres reflektorisch ausgelösten rhytmischen Nystagmus und seine Begleiterscheinungen. (Ein Beitrag zur Physiologie und Pathologie des Bogengangapparates). Monatsschrift für Ohrenheilkunde, 1906; 40: 193-297 [Bárány past pointing test]
- Bárány R. Ueber die vom Ohrlabyrinth ausgelöste Gegenrollung der Augen bei Normalhörenden. Archiv für Ohrenheilkunde, 1906; 68: 1-30. [Bárány caloric test]
- Bárány R. Physiologie und pathologie (funktions-prüfung) des bogengang-apparates beim menschen: klinische studien. 1907 [Bárány chair] [Translation : Physiology and pathology of the semicircular canals. 1910]
- Bárány R. Lärmapparat zum Nachweis einseitiger Taubeheit (Demonstration). Zeitschrift für Ohrenheilkunde, 1908; 56: 287-288 [Bárány’s alarm apparatus]
- Bárány R. Die nervosen Storungen des Cochlear- und Vestibularapparates. In: Handbuch der Neurologie [Lewandowsky M (ed.)] 1910; I(IV): 919-958. [Bárány chair]
- Bárány, R. Der Schwindel und seine Beziehungen zum Bogengangapparat des inneren Ohres. Bogengangapparat u. Kleinhirn. (Historische Darstellung. Eigene Untersuchungen). Naturwissenschaften 1913; 1: 396–401 and 425–428
- Bárány R. Some new methods for functional testing of the vestibular apparatus and the cerebellum (Nobel Lecture, September 11, 1916)
- Bárány R. Diagnose yon Krankheitserscheinungen im Bereiche des Otolithenapparates. Acta Oto-Laryngologica 1920; 2(3): 434-437. [Dix-Hallpike test]
- Although nominated for his Nobel Prize in 1914 he did not receive it until over a year later. During the selection process in 1914, the Nobel Committee for Physiology or Medicine decided that none of the year’s nominations met the criteria as outlined in the will of Alfred Nobel. According to the Nobel Foundation’s statutes, the Nobel Prize can in such a case be reserved until the following year, and this statute was then applied.
- When it was finally announced that the 1914 Nobel prize has been awarded to Bárány, he at that time incarcerated in a prisoner-of-war camp in Russia. After the personal intervention of Prince Carl of Sweden, he was released to receive the prize in 1916
- He was reproached by Austrian colleagues at the Faculty of Medicine in Vienna for having only made incomplete references to the discoveries of other scientists on whose theories his work was based. In 1921 a report was published that dismissed these claims.
- Parsons RP, Segar LH. Barany chair tests and flying ability: A correlation study of 100 naval aviators. JAMA. 1918;70(15):1064-1065
- Torok N. Robert Bárány. JAMA. 1980;244(22):2520.
- Shampo MA, Kyle RA. Robert Bárány. JAMA. 1980;243(19):1914.
- Baloh RW. Robert Bárány and the controversy surrounding his discovery of the caloric reaction. Neurology. 2002;58(7):1094-1099.
- Haas LF. Robert Bárány 1876-1936. J Neurol Neurosurg Psychiatry. 2005; 76(5): 662.
- Pearce JM. Benign paroxysmal vertigo, and Bárány’s caloric reactions. Eur Neurol. 2007;57(4):246-248.
- Cosimi AB. Surgeons and the Nobel Prize. Arch Surg. 2006;141(4):340-348.
- Lopez C, Blanke O. Nobel Prize centenary: Robert Bárány and the vestibular system. Curr Biol. 2014;24(21):R1026-R1028.
- Bracha A, Tan SY. Robert Bárány (1876-1936): the Nobel Prize-winning prisoner of war. Singapore Med J. 2015;56(1):5-6.
- Baloh RW. Vertigo: Five Physician Scientists and the Quest for a Cure. 2016
- Bibliography. Róbert Bárány (1876 – 1936). WorldCat Identities
the person behind the name