Sir William Osler was a man of not inconsiderable talent. A pathologist and clinician. A professor successively at McGill University, the University of Pennsylvania, Johns Hopkins University and Oxford University. Historian and bibliographer of medicine. A naturalist, microscopist, proponent of…
Alfred Russel Wallace did not knowingly study infectious diseases or their microbial causes, but he did travel extensively and repeatedly put himself in the biological line of fire, as evidenced in his many writings.
Fleming’s role in the discovery and subsequent development of penicillin is well-known parable of the importance of serendipity in medical research. Fewer people know anything about the Scots bacteriologist’s earlier discovery of lysosyme or his work on the bacteriology of traumatic wound infection.
Chvostek sign is contraction of facial muscles provoked by lightly tapping over the facial nerve anterior to the ear as it crosses the zygomatic arch.
Corrigan pulse is the excessive visible arterial pulsations in aortic incompetence. Not to be confused with the palpated 'water-hammer pulse'.
Moschcowitz disease (1924) [aka *thrombotic thrombocytopenic purpura (TTP)]. Congenital syndrome characterised by thrombocytopenia, purpura, haemolytic anaemia, hyaline thromboses, renal failure and neurological symptoms.
Cotard syndrome: A rare condition characterized by nihilistic delusions, where a patient believes that they are dead, have missing organs, or have decaying or failing body parts.
Gilbert's syndrome: congenital, benign, chronic, intermittent hyperbilirubinemia. Fluctuating episodes of jaundice in the absence of any specific symptoms, with an excess of unconjugated bilirubin present in the urine.
Anton syndrome: Visual anosognosia or Anton-Babinski syndrome is a rare neurological condition related to cortical blindness. The patients deny their blindness and affirm adamantly that they are capable of seeing.
Heerfordt syndrome: a rare manifestation of sarcoidosis characterized by the presence of fever, facial nerve palsy, parotid gland enlargement, anterior uveitis, and low grade fever
Charcot-Marie-Tooth disease (spinal form of muscular atrophy) is the commonest disease within a group of conditions called Hereditary Motor and Sensory Neuropathies (HMSN).
Duroziez-type murmur observed with the patients arm subjected to various temperatures of water and by applying a subdiastolic pressure below the auscultation site, to help differentiate between aortic insufficiency and peripheral vasodilatation.