
Renal Literature Summaries
Renal Literature Summaries

Renal Literature Summaries

Opioid Withdrawal

Opioid Overdose: miosis; CNS depression; respiratory depression; complications of hypoxia: seizures, dysrrhythmia, brain injury

Paraquat Poisoning; highly toxic herbicide; common agent in suicide in 3rd world; leading single agent causing death from pesticide poisoning in many countries including Sri Lanka

The patient's form a heterogeneous group that requires a systematic approach based on early resuscitation where needed, risk assessment to guide further management and early consideration of the underlying psychosocial issues.

AKI is the entire spectrum of disease (mild -> severe), and can be defined as an abrupt (1 to 7 days) and sustained (more than 24 hours) decrease in kidney function. Mortality of critically patients with acute renal failure is high (50%–60%)

Acute kidney injury (AKI) is a common problem in the critically ill associated with increased morbidity and mortality

AKI can be defined as an abrupt (1 to 7 days) and sustained (more than 24 hours) decrease in kidney function. The ADQI formulated the RIFLE criteria in 2004 to allow for AKI to be objectively and uniformly defined.

Renal Transplant; commonest transplant; anastamosed to common iliac artery and vein in the pelvis. the ureter is plumbed into the bladder; allows ease of access for palpation and biopsy

Dosing is different to non-critically ill patients
Different antimicrobials have different kill characteristics, which can be demonstrated on a concentration vs time graph for antibiotic activity

See RCH Melbourne Guidelines:

ILCOR = International Liaison committee on Resuscitation = conglomerate of resuscitation councils worldwide. Changes in 2010